06 February 2024 : Original article
Immunoprotective Effect of Liver Allograft on Patients with Combined Liver and Kidney Transplantation
Joon-Young Kim
1BCDEF, Hye Bin Kim2BCDEF, Jin-Myung Kim 1BCD, Hye Eun Kwon 1BCD, Young Hoon Kim 1BCD, Youngmin Ko 1BCD, Frances S. Sung 1BCD, Joo Hee Jung 1BC, Chung Hee Baek 3B, Hyosang Kim 3B, Su-Kil Park 3B, Sung Shin 1BCD, Hyunwook Kwon1ABCDEF*
DOI: 10.12659/AOT.942763
Ann Transplant 2024; 29:e942763
Table 4 Baseline and clinical characteristics of propensity score-matched groups.
| KT | LTKT | SMD | |
|---|---|---|---|
| Number of patients | 132 (75.0) | 44 (25.0) | – |
| Mean age (years) | 49.4±11.8 | 50.2±8.2 | 0.074 |
| Female sex | 21 (15.9) | 7 (15.9) | |
| Diabetes mellitus | 44 (33.3) | 16 (36.4) | 0.064 |
| Hypertension | 93 (70.5) | 32 (72.7) | 0.050 |
| Hepatitis B virus | 36 (27.3) | 12 (27.3) | 0.000 |
| Hepatitis C virus | 2 (1.5) | 1 (2.3) | 0.056 |
| Body mass index, kg/m | 21.7±3.8 | 22.0±2.7 | 0.086 |
| ABO-incompatible | 24 (18.2) | 5 (11.4) | −0.193 |
| FCXM positivity | 9 (6.8) | 2 (4.5) | −0.098 |
| HLA-A, B, DR mismatch | 3.2±1.7 | 3.5±1.9 | −0.045 |
| PRA class I | 12.3±24.2 | 11.3±24.2 | −0.043 |
| PRA class II | 12.8±24.8 | 14.0±26.7 | 0.044 |
| Cadaveric donor | 38 (28.8) | 13 (29.5) | −0.017 |
| Living donor | 94 (81.2) | 31 (70.5) | |
| Calcineurin inhibitor | 0.074 | ||
| Tacrolimus | 106 (80.3) | 34 (77.3) | |
| Cyclosporin | 26 (19.7) | 10 (22.7) | |
| Continuous data are presented as means±standard deviations. Categorical data are presented as a number (%). KT – kidney transplantation; LT – liver transplantation; SMD – standardized mean difference; FCXM – flow cytometry crossmatch; PRA – panel reactive antibody; SLKT – simultaneous liver-kidney transplantation. | |||