30 April 2024 : Original article
Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients
Zhenwei Jiang1BCDEF, Caomei Xu1CE, Huan Hou2C, Xuping Yang1D, Minyan Qian1B, Lian Zuo1B, Peipei Wang3B, Qing Qian1D, Yan Jiang1B, Nan Hu1AG*DOI: 10.12659/AOT.943282
Ann Transplant 2024; 29:e943282
Table 1 Clinical characteristics of renal transplant patients before transplantation.
| Characteristics | PTDM (n=37) | Non-PTDM (n=372) | P value |
|---|---|---|---|
| Sex, n (%) | 0.183 | ||
| Male | 28 (75.7) | 241 (64.8) | |
| Female | 9 (24.3) | 131 (35.2) | |
| Age, years | 44.5±10.3 | 38.6±10.0 | <0.001 |
| BMI, kg/m | 23.1±2.4 | 21.4±3.2 | <0.001 |
| HBV, n (%) | 3 (5.1) | 19 (4.6) | 0.697 |
| HCV, n (%) | 0 (0) | 1 (0.3) | >0.999 |
| Magnesium, mmol/L | 0.97±0.21 | 1.02±0.25 | 0.359 |
| Urine protein, n (%) | 36 (97.3) | 335 (90.1) | 0.250 |
| Systolic pressure, mmHg | 146.1±24.6 | 149.6±22.2 | 0.390 |
| Diastolic pressure, mmHg | 89.6±13.9 | 93.4±14.4 | 0.144 |
| FBG, mmol/L | 5.1±0.9 | 5.1±0.9 | 0.843 |
| Total cholesterol, mmol/L | 4.1±1.1 | 4.3±1.3 | 0.397 |
| Triglycerides, mmol/L | 2.0±0.9 | 1.9±1.3 | 0.793 |
| HDL-C, mmol/L | 1.0±0.3 | 1.1±0.4 | 0.062 |
| LDL-C, mmol/L | 2.2±0.8 | 2.2±0.9 | 0.945 |
| Urea, mmol/L | 20.1±6.4 | 19.0±6.5 | 0.333 |
| Serum uric acid, μmol/L | 364.8±109.5 | 358.2±109.1 | 0.731 |
| Serum creatinine, μmol/L | 841.6±212.9 | 908.0±448.6 | 0.381 |
| BMI – body mass index; HBV – hepatitis B virus; HCV – hepatitis C virus; FBG – fasting blood glucose: HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; PTDM – post-transplantation diabetes mellitus; Values are expressed as the mean±standard deviation, number (%); Variables except inpatient days present the baseline value before renal transplantation. | |||