30 April 2024 : Original article
Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients
Zhenwei Jiang1BCDEF, Caomei Xu1CE, Huan Hou2C, Xuping Yang1D, Minyan Qian1B, Lian Zuo1B, Peipei Wang3B, Qing Qian1D, Yan Jiang1B, Nan Hu1AG*DOI: 10.12659/AOT.943282
Ann Transplant 2024; 29:e943282
Table 3 Summary of antibiotic use in patients after renal transplantation.
| Antibiotic class | PTDM (n=37), n (%) | Non-PTDM (n=372), n (%) | P value |
|---|---|---|---|
| Penicillins | 28 (75.7) | 226 (60.8) | 0.074 |
| Second-generation Cephalosporins | 3 (8.1) | 58 (15.6) | 0.223 |
| Third-generation Cephalosporins | 10 (27.0) | 146 (39.2) | 0.144 |
| Carbapenems | 21 (56.8) | 143 (38.4) | 0.030 |
| Oxazolidinones | 17 (45.9) | 122 (32.8) | 0.107 |
| Quinolones | 15 (40.5) | 103 (30.4) | 0.100 |
| Sulfonamides | 5 (13.5) | 24 (6.5) | 0.208 |
| Glycopeptides | 3 (8.1) | 17 (4.6) | 0.581 |
| Aminoglycosides | 2 (5.4) | 14 (3.8) | 0.963 |
| Polymyxins | 1 (2.7) | 8 (2.2) | 0.578 |
| Tetracyclines | 3 (8.1) | 13 (3.5) | 0.349 |
| Macrolides | 1 (2.7) | 4 (1.1) | 0.379 |
| Antibiotics were used to prevent infection during the perioperative period. Each recipient received multiple antibiotics, and the subjects were repeatedly enrolled. Antibiotics were classified by antibiotic class. Values are expressed as the mean±standard deviation and number. | |||