21 May 2024: Original Paper
Liver Transplantation from Brain-Dead Donors with Hepatitis B or C in South Korea: A 2014–2020 Korean Organ Transplantation Registry Data Analysis
Hoonsung Park 12CDEF , Hanyoung Lee 3CDF , Seungmin Baik 4DF , Myoung Soo Kim 5ABG , Jaeseok Yang 6ABG , Jong Cheol Jeong 7ABG , Tai Yeon Koo 8ABG , Deok-Gie Kim 9ABG , Jae-Myeong Lee 3ACDFG*DOI: 10.12659/AOT.943588
Ann Transplant 2024; 29:e943588
Table 1 Donor characteristics.
| HBV(+) donors (n=24) | HCV(+) donor (n=1) | HBV(−)/HCV(−) donors (n=1010) | p valuea) | |
|---|---|---|---|---|
| 49.1±13.1 | 61 | 47.4±16.4 | HBV(+)−HBV(−)/HCV(−): p=0.55 | |
| HBV(+)− HBV(−)/HCV(−): p=0.39 | ||||
| Male | 18 (75%) | 1 (100%) | 658 (65.1%) | |
| Female | 6 (25%) | 0 | 352 (34.9%) | |
| 23.9±3.6 | 29 | 23.1±3.6 | HBV(+)−HBV(−)/HCV(−): p=0.32 | |
| HBV(+)−HBV(−)/HCV(−): p=0.09 | ||||
| Trauma | 6 (25%) | 0 | 336 (33.2%) | |
| Underlying disease progression | 11 (45.8%) | 1 (100%) | 422 (41.8%) | |
| Suicide | 7 (29.2%) | 0 | 146 (14.5%) | |
| Other/unknown | 0 | 0 | 106 (10.5%) | |
| HBV(+)−HBV(−)/HCV(−): p=0.74 | ||||
| Subarachnoid hemorrhage | 9 (37.5%) | 0 | 319 (31.6%) | |
| Intracranial hemorrhage | 5 (20.8%) | 1 (100%) | 293 (29%) | |
| Cerebral infarction | 0 | 0 | 38 (3.7%) | |
| Hypoxic damage | 10 (41.7%) | 0 | 321 (31.8%) | |
| CNS malignancy | 0 | 0 | 4 (0.4%) | |
| Other/unknown | 0 | 0 | 35 (3.5%) | |
| HBV(+)−HBV(−)/HCV(−): p=0.01 | ||||
| Standard donor (by KONOS category) | 11 (45.8%) | 0 | 736 (72.9%) | |
| Marginal donor (by KONOS category)b) | 13 (54.2%) | 1 (100%) | 274 (27.1%) | |
| 19 (79.2%) | 1 (100%) | 768 (76%) | HBV(+)−HBV(−)/HCV(−): p=1 | |
| HBV(+)−HBV(−)/HCV(−): p=1 | ||||
| Whole liver | 24 (100%) | 0 | 937 (92.8%) | |
| Modified Rt. Lobectomy | 0 | 0 | 5 (0.5%) | |
| Extended Rt. Lobectomy (Rt. Lobe with MHV) | 0 | 0 | 18 (1.8%) | |
| Rt. Lobectomy | 0 | 0 | 15 (1.5%) | |
| Lt. Lobectomy | 0 | 0 | 6 (0.6%) | |
| Extended Lt. Lobectomy (Lt. lobe with MHV) | 0 | 0 | 1 (0.1%) | |
| Lt. Lateral segmentectomy | 0 | 0 | 26 (2.5%) | |
| Rt. Posterior sectionectomy | 0 | 0 | 0 | |
| Reduced left lateral or mono-segment | 0 | 0 | 1 (0.1%) | |
| Others | 0 | 1 (100%)c) | 1 (0.1%) | |
| BMI – body mass index; CNS – central nervous system; KONOS – Korean Network for Organ Sharing; Rt – right; Lt – left; MHV – middle hepatic vein. a) b) c) . | ||||