Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Xiaoxuan Wei; Sai Huang; Zhenyang Gu; Jing Liu; Meng Li; Xiangshu Jin; Jian Bo; Fei Li; Yu Jing; Xiaoning Gao; Liping Dou; Daihong Liu; Chunji Gao

doi:10.12659/AOT.943688

02 July 2024 : Original article

Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Xiaoxuan Wei^12ABCDEF, Sai Huang^1ABF, Zhenyang Gu^1ADEF, Jing Liu^1ADEF, Meng Li^1AF, Xiangshu Jin^1AF, Jian Bo^1AF, Fei Li^1A, Yu Jing^1A, Xiaoning Gao^1A, Liping Dou^1AB, Daihong Liu^1A, Chunji Gao^1ADEF*

DOI: 10.12659/AOT.943688

Ann Transplant 2024; 29:e943688

Authors information Article notes Copyright and License information

Introduction Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 2 Incidence of aGVHD.

	TotalN=196	No CH mutationsN=103	With CH mutationsN=93	P
aGVHD grade^*				0.210
No	79 [40.5]	47 [46.1]	32 [34.4]
I	40 [20.5]	20 [19.6]	20 [21.5]
II	53 [27.2]	21 [20.6]	32 [34.4]
III	17 [8.7]	9 [8.8]	8 [8.6]
IV	6 [3.1]	5 [4.9]	1 [1.1]
Data are no. [%] unless otherwise specified. ^* A patient’s data is missing. CH mutation – clonal hematopoiesis-associated mutation; aGVHD – acute graft versus host disease.

Back to the Article

Clonal Hematopoiesis-Associated Gene Mutations Affect Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation in AML Patients

Your Privacy