03 December 2024 : Original article
Hepatopulmonary Syndrome and Liver Transplantation: Impact on Survival and Postoperative Complications
Yin Lai ABCDEF 1,2, Hao-Chien Hung BCD 1,2, Jin-Chiao Lee BCD 1,2, Yu-Chao Wang CDE 1,2, Chih-Hsien Cheng CDE 1,2, Tsung-Han Wu BCD 1,2, Ting-Jung Wu BCD 1,2, Hong-Shiue Chou CDE 1,2, Kun-Ming Chan DEF 1,2, Wei-Chen Lee DEF 1,2, Chen-Fang Lee ACDEF 1,2*DOI: 10.12659/AOT.945297
Ann Transplant 2024; 29:e945297
Table 2 Comparisons of clinical characteristics and postoperative outcomes.
| General information | Non-HPS, N=77 | HPS, N=104 | P value |
|---|---|---|---|
| Delayed extubation | 0.028 | ||
| No (≤48 hours) | 69 (89.6%) | 81 (77.9%) | |
| Yes (>48 hours) | 8 (10.4%) | 23 (22.1%) | |
| Re-intubation within one week after extubation | 2 (3.9%) | 12 (11.5%) | 0.045 |
| ICU stay (day) | 15.0±9.9 | 13.6±9.4 | 0.409 |
| Postop pleural effusion or pulmonary edema (within one week) | 62 (80.5%) | 83 (79.8%) | 1.000 |
| Post-LT chest pigtail insertion | 8 (10.4%) | 17 (16.3%) | 0.012 |
| Postop pneumonia (within one month) | 9 (11.7%) | 21 (20.2%) | 0.158 |
| Post CMV infection(within one month) | 25 (32.5%) | 33 (31.7%) | 1.000 |
| Hospital stay (day) | 31.4±18.4 | 36.0±30.9 | 0.097 |
| Re-laparotomy | 4 (5.2%) | 4 (3.8%) | 0.725 |
| Early allograft dysfunction | 14 (18.2%) | 25 (24.0%) | 0.367 |
| 30-day mortality | 4 (5.2%) | 6 (5.8%) | 1.000 |
| Overall survival (Mean±SD, month) | 63.36±3.8 | 69.82±3.1 | 0.332 |
| HPS – hepatopulmonary syndrome; ICU – Intensive Care Unit; LT – liver transplantation; CMV – cytomegalovirus. | |||