Predictive Model for Post-Transplant Renal Fibrosis Using Ultrasound Shear Wave Elastography

29 October 2024 : Original article

Juan Wang^1BE, Jianghong Chen^2CD, Yuewei Yin^3BF, Yuena Zhang^1C, Yulin Ma^1AG*

DOI: 10.12659/AOT.945699

Ann Transplant 2024; 29:e945699

Introduction Material and Methods Results Discussion Conclusions References

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Table 2 Univariate and multivariate analysis of renal fibrosis in the training cohort.

Characteristic	UnivariateOR (95% CI)	p value	MultivariateOR (95% CI)	p value
Age (years)	1.327 (1.238–1.920)	0.000	1.341 (1.232–1.643)	0.026
Sex (Male/Female)	0.834 (0.322–1.457)	0.263
BMI (kg/m)	2.284 (0.267–3.391)	0.074
Smoking (yes/no)	1.327 (0.114–2.436)	0.164
Drinking (yes/no)	0.825 (0.738–1.445)	0.084
Type 2 diabetes (yes/no)	2.381 (0.235–1.872)	0.381
TST (months)	2.835 (0.267–0.721)	0.000	2.381 (0.135–0.724)	0.017
Donor type (living/decreasing)	0.389 (0.638–1.482)	0.482
Urine volume (mL)	0.352 (0.356–1.456)	0.743
Resting heart rate (times/min)	1.535 (0.643–2.643)	0.081
Systolic blood pressure (mmHg)	2.534 (0.083–3.041)	0.129
Diastolic pressure (mmHg)	1.429 (0.172–1.009)	0.302
Scr (μmol/L)	3.381 (2.216–4.525)	0.021	3.354 (2.325–3.947)	0.033
Urea nitrogen (mg/dL)	2.539 (0.416–1.832)	0.236
Proteinuria (yes/no)	1.742 (0.281–1.425)	0.056
Hematuria (yes/no)	1.856 (0.418–2.948)	0.114
GFR (mL/min)	2.284 (0.267–3.391)	0.017	2.284 (0.267–3.391)	0.000
Hydronephrosis	1.924 (0.873–2.349)	0.307
Echogenicity uniformity/nonuniformity	0.343 (0.342–1.928)	0.282
Parenchymal echogenicity (hyperechoic/nonhyperechoic)	2.430 (0.282–3.129)	0.219
Kidney length (cm)	1.034 (0.739–1.489)	0.059
Kidney width (cm)	1.173 (0.635–1.380)	0.068
Parenchyma thickness (cm)	0.439 (0.490–3.058)	0.108
PSV of arcuate artery (cm/s)	0.832 (0.602–2.043)	0.283
RI of arcuate artery	3.343 (0.562–2.407)	0.145
Emean (kPa)	2.284 (0.267–3.391)	0.003	2.284 (0.267–3.391)	0.029

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