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18 March 2025 : Original article  

Effect of a Nursing Program on Anxiety, Depression, and Insomnia in Patients After Liver Transplantation: A Randomized Controlled Trial

Shuang-Mei Xi1ABCDEF, Yan-Mei Gu1ABCDEF, Hui-Min Guo2ABCDEF, Xin Liu1ABCDEF, Yu-Lin Zheng1ABCDEF, Guang-Ming Li3ABCDEFG*, Li-Li Zhang2ABCDEF

DOI: 10.12659/AOT.947351

Ann Transplant 2025; 30:e947351

Table 3 Time effects and intervention effects on anxiety, depression, and insomnia.

TimeAnxiety score (M±SD)Depression score (M±SD)Sleep quality score (M±SD)
Intervention group0–60 days24.14±3.5161.51±4.2314.34±2.12
61–120 days22.21±1.9355.32±5.2412.64±1.87
121–180 days20.69±4.3142.82±4.1710.68±2.32
181–360 days16.46±4.0638.74±5.719.12±4.23
Control group0–60 days39.43±5.1269.15±8.7218.16±4.12
61–120 days33.12±4.2165.28±6.1317.13±3.82
121–180 days32.61±4.1554.39±5.8113.11±5.17
181–360 days26.67±5.6350.22±7.3311.82±4.23
8.77116.8218.166
<0.001<0.001<0.001
4.2839.27810.827
0.008<0.001<0.001
1.2831.3840.382
0.0970.1280.334

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358