Effects of Donor-Recipient Race Matching on Kidney Transplant Survival

03 June 2025 : Original article

Marie Chisholm-Burns

^{ABDEF 1*}, Christina Spivey

^{ABCDEF 1}, Richard Formica^{ADEF 2}

DOI: 10.12659/AOT.947720

Ann Transplant 2025; 30:e947720

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Table 3 Graft survival outcomes (n=7) [2,5,24–28].

Study	Reference group (D/R pairing)	D/R pairing	Graft survival or loss outcome, D/R pairing vs reference group
Gaston et al 1992 []⁵	White-Black	Black-Black	p=.07 (NS)
LeClaire et al 2021 []²	White-White	Mismatched-White	NS [HR: 0.958 (95% CI 0.913–1.006), p=.084]
LeClaire et al 2021 []²	Black-Black	Mismatched-Black	Black-Black pairing had decreased graft survival [HR: 1.118 (95% CI 1.066–1.172), p<.001]
Meier-Kriesche et al 2000 []²⁴	White-White	Black-White	Black-White pairing had increased risk of graft loss [RR: 1.26, 95% CI 1.12–1.421; p=.0001]
Opelz et al 1977 []²⁵	White-White	Black-Black	Black-Black pairing had decreased graft survival (p<.001)
	White-White	Black-White	Black-White pairing had decreased graft survival (p<.005)
	White-White	White-Black	White-Black pairing had decreased graft survival (p<.001)
Perdue & Terasaki 1982 []²⁶	White-White	White-Black	White-Black pairing had decreased graft survival^b
Tiwari et al 1987 []²⁷	White-White	White-Black	White-Black pairing had decreased graft survival^b
Vincenti et al 1978 []²⁸	White-White	Mismatched-White	NS (p value not reported)
Vincenti et al 1978 []²⁸	Black-Black	Mismatched-Black	NS (p value not reported)
CI – confidence interval; D/R – donor-recipient; HR – hazard ratio; NS – not significant; RR – risk ratio. ^a Caveat: Study did not specify if patient population included pediatrics; ^b Article indicates statistical significance but does not report values.

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