Comparative Prognostic Performance of Pretransplant AARC, CLIF-C ACLF, and MELD-Na Scores for 90-Day Mortality After Liver Transplantation in Patients With EASL-CLIF Acute-on-Chronic Liver Failure

08 September 2026 : Clinical Research

Nguyen Thai Cuong^{ABCDEF 1}, Le Xuan Duong^{ABCDEF 1}, Nguyen Chi Tam^{BDE 2}, Nam Van Do

^{BDE 2}, Ngo Dinh Trung^{ACDEF 2*}

DOI: 10.12659/AOT.954888

Ann Transplant 2026; 31:e954888

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Table 2 Prognostic performance for 90-day mortality.

Score	AUROC (95% CI)	Firth OR per 1 SD (95% CI)	P value	Cox HR per 1 SD (95% CI)	P value
AARC	0.654 (0.491–0.799)	1.63 (0.88–3.03)	0.121	1.63 (0.93–2.87)	0.089
CLIF-C ACLF	0.755 (0.562–0.917)	2.72 (1.31–5.64)	0.007	2.89 (1.47–5.66)	0.002
MELD-Na	0.714 (0.550–0.854)	2.17 (1.13–4.17)	0.019	2.05 (1.15–3.66)	0.016
ORs and HRs are reported for each 1-standard-deviation increase. In this cohort, 1 standard deviation corresponded to 2.39 AARC points, 11.05 CLIF-C ACLF points, and 6.17 MELD-Na points. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; HR, hazard ratio; OR, odds ratio; SD, standard deviation.

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