08 September 2026 : Clinical Research
Comparative Prognostic Performance of Pretransplant AARC, CLIF-C ACLF, and MELD-Na Scores for 90-Day Mortality After Liver Transplantation in Patients With EASL-CLIF Acute-on-Chronic Liver Failure
Nguyen Thai Cuong ABCDEF 1, Le Xuan Duong ABCDEF 1, Nguyen Chi Tam BDE 2, Nam Van Do
BDE 2, Ngo Dinh Trung ACDEF 2*
DOI: 10.12659/AOT.954888
Ann Transplant 2026; 31:e954888
Table 4 Sensitivity analyses for 90-day mortality.
| Analysis | AARC AUROC | CLIF-C ACLF AUROC | MELD-Na AUROC | Comment |
|---|---|---|---|---|
| Primary recalculated scores | 0.654 (0.491–0.799) | 0.755 (0.562–0.917) | 0.714 (0.550–0.854) | n = 78; 14 deaths; primary analysis |
| Originally recorded scores | 0.613 | 0.732 | 0.647 | n = 78; 14 deaths; descriptive quality-control analysis |
| Living-donor recipients only | 0.639 | 0.715 | 0.721 | n = 70; 12 deaths; descriptive restricted-cohort analysis |
| Conditioned on survival beyond postoperative day 7 | 0.578 | 0.666 | 0.696 | n = 74; 10 subsequent deaths through day 90; descriptive landmark analysis |
| Any recorded CRRT satisfies the MELD-Na dialysis rule | - | - | 0.725 | n = 78; 14 deaths; descriptive alternative MELD-Na calculation |
| AUROC values refer to 90-day mortality. The primary recalculated-score row includes percentile-bootstrap 95% confidence intervals. All other sensitivity-analysis AUROCs are descriptive point estimates; no pairwise hypothesis tests were performed. Small numerical differences should not be interpreted as evidence of stable comparative performance. CRRT, continuous renal replacement therapy. | ||||