22 November 2019: Letter To Editor
Antithymocyte Globulin: Indiscriminate Use and Complications
Taqi Khan EF 1*, Irfan Mirza F 2, Nisar Anwar E 2
DOI: 10.12659/AOT.919655
Ann Transplant 2019; 24:605-607
Abstract
ABSTRACT: The safety profile of rATG is impressive, with its use in 40% of inductions in living donor transplants in the US, with a reduced incidence of acute rejection, a low incidence of CMV infections with universal prophylaxis and enabling steroid sparing regimes.
Keywords: Graft Rejection, Immunosuppressive Agents, Kidney Transplantation, Antilymphocyte Serum
References
1. Bayraktar A, Catma Y, Akyildiz A, Infectious complications of induction therapies in kidney transplantation: Ann Transplant, 2019; 24; 412-17, pmid: 31296835
2. Reusing JO, Feitosa EB, Agena F, CMV prophylaxis in seropositive renal transplant recipients receiving Thymoglobulin induction therapy: Outcome and risk factors for late CMV disease: Transpl Infect Dis, 2018; 20; e12929, pmid: 29809309
3. Gaber AO, Monaco AP, Russell JA, Rabbit antithymocyte globulin (Thymoglobulin) 25 years and new frontiers in solid organ transplantation and hematology: Drugs, 2010; 70; 691-732, pmid: 20394456
4. Gaber AO, Matas AJ, Henry ML, Antithymocyte globulin induction in living donor renal transplant recipients: final report of the TAILOR registry: Transplantation, 2012; 94(4); 331-37, pmid: 22850297
5. Hardinger KL, Schnitzler MA, Koch MJ, Thymoglobulin induction is safe and effective in live-donor renal transplantation: A single center experience: Transplantation, 2006; 81; 1285-90, pmid: 16699456
6. Mohty M, Bacigalupo A, Saliba F, New directions for rabbit antithymocyte globulin in solid organ transplants, stem cell transplants and autoimmunity: Drugs, 2014; 74(14); 1605-34, pmid: 25164240
7. Brennan DC, Daller JA, Lake KD, Rabbit antithymocyte globulin versus basiliximab in renal transplantation: N Engl J Med, 2006; 355; 167
8. : Scientific registry of transplant recipients Available at http://www.ustransplant.org
9. Goggins WC, Pascual MA, Powelson JA, A prospective, randomized clinical trial of intraoperative versus post-operative thymoglobulin in adult cadaveric renal transplant recipients: Transplantation, 2003; 76(5); 798-802, pmid: 14501856
In Press
Original article
Diagnostic Utility of FAR1 Methylation Levels in Hepatocellular Carcinoma Patients Undergoing Liver Transpl...Ann Transplant In Press; DOI: 10.12659/AOT.951568
Original article
Inferior Long-Term Outcome of Fatty Liver Allografts After Orthotopic Liver TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.950589
Database Analysis
Identification and Validation of Liver Transplantation-Induced Acute Lung Injury Biomarkers Using a Bioinfo...Ann Transplant In Press; DOI: 10.12659/AOT.950289
Original article
Survival and Recurrence in Liver Transplant Patients With Intrahepatic Cholangiocarcinoma and Hepatocellula...Ann Transplant In Press; DOI: 10.12659/AOT.950997
Most Viewed Current Articles
24 Aug 2021 : Review article 18,372
Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future PerspectivesDOI :10.12659/AOT.931664
Ann Transplant 2021; 26:e931664
05 Apr 2022 : Original article 14,731
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
22 Nov 2022 : Original article 14,244
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
29 Dec 2021 : Original article 13,752
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588