The significant improvements in the management of immunosuppression over the last decades have been a major impetus for the expansion of organ transplantation. This success has led to a proliferation in the number of transplant programs throughout the world. However, at the present time, the number of transplantation procedures tends to reach a plateau in most countries, with increasing delay for transplantation for patients on the waiting list. Donor organ availability appears to be the single most important factor responsible for this phenomenon.

Keywords: Immunosuppression, Transplantation