28 September 2010
Merkel cell carcinoma in a kidney transplant patient: Case report and update on management
Ilona Kurnatowska, Anna Zawiasa, Joanna Narbutt, Malgorzata Wagrowska-Danielewicz, Marek Stempien, Michal NowickiAnn Transplant 2010; 15(3): 66-70 :: ID: 881168
Abstract
Background: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor. Its incidence is markedly greater in immunocompromised patients. MCC is found almost exclusively on sun-exposed facial sites.
Case Report: We describe a case of a 62-year-old male renal transplant recipient who was diagnosed with MCC with primary atypical localization on the buttock 5 years after transplantation. Despite the conversion from CsA to mTOR inhibitor, surgical operation, and radiotherapy, the patient developed disseminated skin lesions and died due to multiple metastases.
Conclusions: This case emphasizes the importance of screening for MCC in atypical localizations in transplant organ recipients
Keywords: renal transplantation, merkel cell carcinoma, skin cancers, immunosuppressive therapy
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