12 April 2022: Letter To Editor
Pancreas Allograft Thrombosis as a Post-COVID-19 Complication in a Diabetic Patient After Pancreas Transplantation
Karolina Kędzierska-Kapuza1ABCDEF*, Grzegorz Witkowski
DOI: 10.12659/AOT.935863
Ann Transplant 2022; 27:e935863
Abstract
ABSTRACT: Arterial and venous thrombosis of pancreatic allografts is a rare complication in the late post-transplantation period. In addition to traditional thrombosis risk factors, SARS-CoV-2 infection predisposes patients to thrombotic diseases in both arterial and venous vessels. Transplant patients with a history of COVID-19 should be carefully monitored for arterial embolism and graft vein thrombosis. Early detection of this complication in patients after transplantation allows a chance to save the organ. Thromboprophylaxis with low molecular weight heparin is of great importance.
Keywords: COVID-19, Embolism and Thrombosis, Pancreas Transplantation, Allografts, Diabetes Mellitus, Type 1, Humans, Pancreas, Thrombosis
Conclusions
Transplant patients who have experienced COVID-19 should be carefully monitored for the occurrence of graft arterial and vein embolism. Early detection of these complications in patients after organ transplantation gives an opportunity to save the organ. Thromoprophylaxis with low molecular weight heparin is highly important and should be continued in high-risk patients (obese, with persistent d-dimer levels >1000) for a minimum of 2 weeks (preferably 4–6 weeks) after reaching the convalescent status.
References
1. Haldane V, De Foo C, Abdalla SM, Health systems resilience in managing the COVID-19 pandemic: Lessons from 28 countries: Nat Med, 2021; 27; 964-80
2. https://www.statista.com/statistics/1104709/coronavirus-deaths-worldwide-per-million-inhabitants/
3. Goldman IA, Ye K, Scheinfeld MH, Lower-extremity arterial thrombosis associated with COVID-19 is characterized by greater thrombus burden and increased rate of amputation and death: Radiology, 2020; 297; E263-69
4. Wang T, Chen R, Liu C, Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19: Lancet Haematol, 2020; 7; e362-63
5. Kędzierska-Kapuza K, Zielińska D, Matejak-Górska M, Durlik M, The course of SARS-CoV-2 in a patient after a recent kidney transplant: A literature review on COVID-19 therapy: Transplant Proc, 2021; 53; 1194-201
6. Tantisattamo E, Dafoe DC, Ferrey AJ, Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient: Clin Nephrol Case Stud, 2021; 26(9); 93-104
7. Xu JJ, Samaha D, Mondhe S, Renal infarct in a COVID-19-positive kidney-pancreas transplant recipient: Am J Transplant, 2020; 20; 3221-24
In Press
17 May 2023 : Original article
Results of Liver Retransplantation After Rescue Hepatectomy: A Single-Center StudyAnn Transplant In Press; DOI: 10.12659/AOT.939557
10 May 2023 : Case report
Outcomes from a Single Transplant Center of 5 Pediatric Cases of Domino Liver Transplantation from Live Don...Ann Transplant In Press; DOI: 10.12659/AOT.939893
Most Viewed Current Articles
24 Aug 2021 : Review article
Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future PerspectivesDOI :10.12659/AOT.931664
Ann Transplant 2021; 26:e931664
26 Jan 2022 : Review article
Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive ModelsDOI :10.12659/AOT.934924
Ann Transplant 2022; 27:e934924
29 Dec 2021 : Original article
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860