Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

12 April 2022: Letter To Editor  

Pancreas Allograft Thrombosis as a Post-COVID-19 Complication in a Diabetic Patient After Pancreas Transplantation

Karolina Kędzierska-Kapuza1ABCDEF*, Grzegorz Witkowski ORCID logo1BDE, Katarzyna Baumgart-Gryn2E, Marek Durlik1ABG

DOI: 10.12659/AOT.935863

Ann Transplant 2022; 27:e935863



ABSTRACT: Arterial and venous thrombosis of pancreatic allografts is a rare complication in the late post-transplantation period. In addition to traditional thrombosis risk factors, SARS-CoV-2 infection predisposes patients to thrombotic diseases in both arterial and venous vessels. Transplant patients with a history of COVID-19 should be carefully monitored for arterial embolism and graft vein thrombosis. Early detection of this complication in patients after transplantation allows a chance to save the organ. Thromboprophylaxis with low molecular weight heparin is of great importance.

Keywords: COVID-19, Embolism and Thrombosis, Pancreas Transplantation, Allografts, Diabetes Mellitus, Type 1, Humans, Pancreas, Thrombosis


Transplant patients who have experienced COVID-19 should be carefully monitored for the occurrence of graft arterial and vein embolism. Early detection of these complications in patients after organ transplantation gives an opportunity to save the organ. Thromoprophylaxis with low molecular weight heparin is highly important and should be continued in high-risk patients (obese, with persistent d-dimer levels >1000) for a minimum of 2 weeks (preferably 4–6 weeks) after reaching the convalescent status.


1. Haldane V, De Foo C, Abdalla SM, Health systems resilience in managing the COVID-19 pandemic: Lessons from 28 countries: Nat Med, 2021; 27; 964-80

2. https://www.statista.com/statistics/1104709/coronavirus-deaths-worldwide-per-million-inhabitants/

3. Goldman IA, Ye K, Scheinfeld MH, Lower-extremity arterial thrombosis associated with COVID-19 is characterized by greater thrombus burden and increased rate of amputation and death: Radiology, 2020; 297; E263-69

4. Wang T, Chen R, Liu C, Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19: Lancet Haematol, 2020; 7; e362-63

5. Kędzierska-Kapuza K, Zielińska D, Matejak-Górska M, Durlik M, The course of SARS-CoV-2 in a patient after a recent kidney transplant: A literature review on COVID-19 therapy: Transplant Proc, 2021; 53; 1194-201

6. Tantisattamo E, Dafoe DC, Ferrey AJ, Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient: Clin Nephrol Case Stud, 2021; 26(9); 93-104

7. Xu JJ, Samaha D, Mondhe S, Renal infarct in a COVID-19-positive kidney-pancreas transplant recipient: Am J Transplant, 2020; 20; 3221-24

In Press

15 Mar 2024 : Review article  

Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...

Ann Transplant In Press; DOI: 10.12659/AOT.941185  

18 Mar 2024 : Original article  

Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of R...

Ann Transplant In Press; DOI: 10.12659/AOT.943282  

20 Mar 2024 : Original article  

Transplant Nephrectomy: A Comparative Study of Timing and Techniques in a Single Institution

Ann Transplant In Press; DOI: 10.12659/AOT.942252  

28 Mar 2024 : Original article  

Association Between FEV₁ Decline Rate and Mortality in Long-Term Follow-Up of a 21-Patient Pilot Clinical T...

Ann Transplant In Press; DOI: 10.12659/AOT.942823  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358