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12 April 2022: Letter To Editor  

Pancreas Allograft Thrombosis as a Post-COVID-19 Complication in a Diabetic Patient After Pancreas Transplantation

Karolina Kędzierska-Kapuza1ABCDEF*, Grzegorz Witkowski ORCID logo1BDE, Katarzyna Baumgart-Gryn2E, Marek Durlik1ABG

DOI: 10.12659/AOT.935863

Ann Transplant 2022; 27:e935863



ABSTRACT: Arterial and venous thrombosis of pancreatic allografts is a rare complication in the late post-transplantation period. In addition to traditional thrombosis risk factors, SARS-CoV-2 infection predisposes patients to thrombotic diseases in both arterial and venous vessels. Transplant patients with a history of COVID-19 should be carefully monitored for arterial embolism and graft vein thrombosis. Early detection of this complication in patients after transplantation allows a chance to save the organ. Thromboprophylaxis with low molecular weight heparin is of great importance.

Keywords: COVID-19, Embolism and Thrombosis, Pancreas Transplantation


Transplant patients who have experienced COVID-19 should be carefully monitored for the occurrence of graft arterial and vein embolism. Early detection of these complications in patients after organ transplantation gives an opportunity to save the organ. Thromoprophylaxis with low molecular weight heparin is highly important and should be continued in high-risk patients (obese, with persistent d-dimer levels >1000) for a minimum of 2 weeks (preferably 4–6 weeks) after reaching the convalescent status.


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2. https://www.statista.com/statistics/1104709/coronavirus-deaths-worldwide-per-million-inhabitants/

3. Goldman IA, Ye K, Scheinfeld MH, Lower-extremity arterial thrombosis associated with COVID-19 is characterized by greater thrombus burden and increased rate of amputation and death: Radiology, 2020; 297; E263-69

4. Wang T, Chen R, Liu C, Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19: Lancet Haematol, 2020; 7; e362-63

5. Kędzierska-Kapuza K, Zielińska D, Matejak-Górska M, Durlik M, The course of SARS-CoV-2 in a patient after a recent kidney transplant: A literature review on COVID-19 therapy: Transplant Proc, 2021; 53; 1194-201

6. Tantisattamo E, Dafoe DC, Ferrey AJ, Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient: Clin Nephrol Case Stud, 2021; 26(9); 93-104

7. Xu JJ, Samaha D, Mondhe S, Renal infarct in a COVID-19-positive kidney-pancreas transplant recipient: Am J Transplant, 2020; 20; 3221-24

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358