Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

15 January 2004 : Original article  

Effects of Chemical Composition of Titanium Material Surface on SAMs Formation by Functional Groups of Alkanethiol and Alkanesilanes

C S Kim, K Shin, D H Lee, B C Pak

Ann Transplant 2004; 9(1A): 48-53 :: ID: 15633

Abstract

Self-assembled monolayers (SAMs) have become an essential technique for biochemical modification of a biomaterial surface using specific peptides. Previous studies reported effects of their terminal functionalities including organic molecules on apatite formation in a simulated body fluid. Biological responses are influenced by the surface chemical characteristics of SAMs as well. This study investigated the adsorption behavior of alkanethiol and two alkanesilanes on modified titanium surfaces using an electrochemical quartz crystal nanobalance (EQCN). The formation of SAMs on three working electrode surfaces: Au coated Ti, commercialized pure Ti (c.pTi) and TiO2 were also examined. The resolution limit obtained for the constructed EQCN was about 0.1 ng. The mass change ratio on the surfaces versus immersion time was investigated using EQCN. The quantity of Thiol-I SAM adsorbed on c.pTi is about 67% compared with the quantity formed on Au coated titanium substrate. Contrarily, there was no SAM formation on the TiO2 surface with a thick titanium oxide layer obtained by the electrochemical oxidation method. The SAM amounts (for organosilanes) adsorbed on TiO2 surfaces of Silane-I[ (CH3O)3Si(SH2)3NHCH2CH2NH2)] and Silane-II[H2N(CHS)3Si(OCH3)3] were approximately 19% and 14% more than that of c.pTi. The results obtained in this study show that by altering titanium surface chemistry and introducing functional groups, titanium surfaces may be modified into functional bioactive surfaces and can be used in the same way as the Au substrate.

Keywords: Titanium, Surface Modification, Alkanethiol, Organosilane, EQCN

Add Comment 0 Comments

In Press

14 Mar 2024 : Case report  

Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...

Ann Transplant In Press; DOI: 10.12659/AOT.942358  

15 Mar 2024 : Review article  

Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...

Ann Transplant In Press; DOI: 10.12659/AOT.941185  

18 Mar 2024 : Original article  

Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of R...

Ann Transplant In Press; DOI: 10.12659/AOT.943282  

20 Mar 2024 : Original article  

Transplant Nephrectomy: A Comparative Study of Timing and Techniques in a Single Institution

Ann Transplant In Press; DOI: 10.12659/AOT.942252  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358