Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

15 January 2004 : Original article  

Effects of Chemical Composition of Titanium Material Surface on SAMs Formation by Functional Groups of Alkanethiol and Alkanesilanes

C S Kim, K Shin, D H Lee, B C Pak

Ann Transplant 2004; 9(1A): 48-53 :: ID: 15633

Abstract

Self-assembled monolayers (SAMs) have become an essential technique for biochemical modification of a biomaterial surface using specific peptides. Previous studies reported effects of their terminal functionalities including organic molecules on apatite formation in a simulated body fluid. Biological responses are influenced by the surface chemical characteristics of SAMs as well. This study investigated the adsorption behavior of alkanethiol and two alkanesilanes on modified titanium surfaces using an electrochemical quartz crystal nanobalance (EQCN). The formation of SAMs on three working electrode surfaces: Au coated Ti, commercialized pure Ti (c.pTi) and TiO2 were also examined. The resolution limit obtained for the constructed EQCN was about 0.1 ng. The mass change ratio on the surfaces versus immersion time was investigated using EQCN. The quantity of Thiol-I SAM adsorbed on c.pTi is about 67% compared with the quantity formed on Au coated titanium substrate. Contrarily, there was no SAM formation on the TiO2 surface with a thick titanium oxide layer obtained by the electrochemical oxidation method. The SAM amounts (for organosilanes) adsorbed on TiO2 surfaces of Silane-I[ (CH3O)3Si(SH2)3NHCH2CH2NH2)] and Silane-II[H2N(CHS)3Si(OCH3)3] were approximately 19% and 14% more than that of c.pTi. The results obtained in this study show that by altering titanium surface chemistry and introducing functional groups, titanium surfaces may be modified into functional bioactive surfaces and can be used in the same way as the Au substrate.

Keywords: Titanium, Surface Modification, Alkanethiol, Organosilane, EQCN

0 Comments

In Press

04 Aug 2022 : Original article  

Long-Term Patency of All-in-One Sleeve Patch Graft Venoplasty in 16 Patients Who Underwent Living Donor Liv...

Ann Transplant In Press; DOI: 10.12659/AOT.936888  

22 Jul 2022 : Original article  

Diagnostic Role of Tumor Markers for Hepatocellular Carcinoma in Liver Transplantation Candidates: An Analy...

Ann Transplant In Press; DOI: 10.12659/AOT.936937  

22 Jul 2022 : Original article  

Development of a Novel Model for Predicting Postoperative Short-Term Outcome in Patients with Hepatitis B-R...

Ann Transplant In Press; DOI: 10.12659/AOT.936732  

22 Jul 2022 : Original article  

Leucine-Rich Alpha-2-Glycoprotein (LRG-1) as a Potential Kidney Injury Marker in Kidney Transplant Recipients

Ann Transplant In Press; DOI: 10.12659/AOT.936751  

Most Viewed Current Articles

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

24 Jul 2020 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358