28 June 2005 : Research paper
Longitudinal Study of Renal Function in Pediatric Liver Transplant RecipientsP Kalicinski, M Szymczak, E Smirska, J Pawlowska, M Teisseyre, A Kaminski, D Broniszczak, A Lembas, J Klimaszewski
Ann Transplant 2005; 10(2): 53-58 :: ID: 16816
Objectives: Study was performed to evaluate prospectively long-term renal function in pediatric liver transplant recipients.
Methods: In 50 children aged 1-18 years, renal function tests (sCr, GFR, ERPF, Cr clearance, renal Doppler ultrasound, ABPM) have been performed before and several times during 36 months follow-up after liver transplantation.
Results: Signifficant reduction of renal filtration function was found in studied children (increase of sCr, decrease of GFR, ERPF, Cr clearance) within 12 months after transplantation, which did not progress further in most children after this time. None of patients progressed to stage 4 or 5 renal failure according to CKD. Schwartz formula was not found reliable in assessing renal function in children after liver transplantation. There was no difference in renal function according to cyclosporine or tacrolimus treatment, however arterial hypertension was more common in cyclosporine treated group.
Conclusions: Although renal damage may be a problem for an individual chuild after liver transplantation, majority of children have stable renal function 36 months after Tx. DTPA GFR should be performed yearly in all children until adulthood not to overlook progression of renal injury.
Keywords: Adolescent, Blood Pressure, Blood Pressure, Child, Child, Child, Preschool, Glomerular Filtration Rate, Hemodynamics, Immunosuppressive Agents - therapeutic use, Infant, Kidney - physiopathology, Kidney Failure, Chronic - prevention & control, Kidney Function Tests, Liver Transplantation, Liver Transplantation, Longitudinal Studies, Prospective Studies, Renal Circulation, Risk Assessment
17 May 2023 : Original articleResults of Liver Retransplantation After Rescue Hepatectomy: A Single-Center Study
Ann Transplant In Press; DOI: 10.12659/AOT.939557
10 May 2023 : Original articleIncidence of Thromboembolic Complications Following Kidney Transplantation with Short and Extended Aspirin ...
Ann Transplant In Press; DOI: 10.12659/AOT.939143
Most Viewed Current Articles
24 Aug 2021 : Review articleNormothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives
Ann Transplant 2021; 26:e931664
26 Jan 2022 : Review articleRecurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models
Ann Transplant 2022; 27:e934924
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
15 Mar 2022 : Case reportCombined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...
Ann Transplant 2022; 27:e935860