Abstract

Purpose: To compare complication rates of telescoped versus end-to-end bronchial anastomoses in single and bilateral lung transplantation. Methods: One hundred and thirty adult lung transplant recipients were evaluated during a seven-year period for the presence of three types of major bronchial anastomotic complications (ischemia, dehiscence, and severe stenosis). Surgical technique, clinical course, and mortality in all patients were reviewed retrospectively. Results: The three major complications, ischemia, dehiscence, and severe stenosis, were observed in 13 (32%), 10 (24%), and 13 (32%), respectively, of 41 telescoped bronchial anastomoses. In contrast, ischemia, dehiscence, and severe stenosis, occurred in 25 (19%), 14 ( I0%), and II (8%) of 135 end-to end anastomoses. These differences were statistically significant for the occurrence of dehiscence and severe stenosis (p=0.0350 and 0.0004, respectively), and not statistically significant for ischemia (p=0.0846). Five (12%) telescoped anastomoses required stent placement as compared with six (4%) end-to end anastomoses (p=0.1313). Early postoperative pneumonia was more common in the telescoped anastomosis group (57%) as compared to the end-to-end group (35%; p=0.027 I). There was a trend to shorter survival in the telescoped anastomosis group (mean survival 1172-z.149 d) as compared to the end-to-end group (mean survival I542-z. 126 d), but these differences did not achieve statistical significance (p=0.2400). Conclusion: In single and bilateral lung transplants, telescoped anastomoses are associated with a higher incidence of bronchial anastomotic
complications and postoperative pneumonia than end-to-end anastomoses.

Keywords: Bronchoscopy, bronchial dehiscence, Lung, Transplantation, bronchialstenosis