Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

09 June 2000

Cellula rImmunology Markers Postransplantation Predictive of Long-Term Graft Outcome

Nancy L Reinsmoent, Annette M Jackson, Angelica DeOliveira, Arthur J Matas, Kristen Gillingham, Frances E Ward

Ann Transplant 2000; 5(2): 50-60 :: ID: 497526

Abstract

Identification of immune parameters that predict longterm graft outcome would aid in identifying those recipients at low versus high risk for immune complications and chronic rejection. Those recpients at low risk presumably could have their immunosuppression successfully lowered or even weaned thereby avoiding the many side effects of immunosuppressive therapy. Recipients who are at high risk for chronic rejection may benefit from changing or even increasing the immunosuppressive therapy. This article focuses on using cellular assays to monitor changes, quantitative and qualitative, in the T-cell recognition process during the posttransplant period, as a means to predict long-term graft outcome. We have focused our studies on the cellular immune parameter of donor antigen-specific hyporeactivity to determine whether we can predict long-term graft outcome for all solid organ recipients [1-8]...

Keywords: MLC, chronic rejection, donor-specific non-responsivness, limiting dilution

0 Comments

Most Viewed Current Articles

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

24 Aug 2021 : Review article  

Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives

DOI :10.12659/AOT.931664

Ann Transplant 2021; 26:e931664

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358