Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

09 March 2001

Evaluating the Competence of Venous Valves Preserved with Denaturationin Cold Ischaemia

M Dunal, M Kruk, M Trochimczuk, G Krasowski, M Geremek, K Chakkour

Ann Transplant 2001; 6(1): 23-25 :: ID: 497570


Aim of study:The aim of this study was to evaluate the competence of venous valves preserved with denaturation in cold ischaemia. Material and method: Eight segments of saphenous veins with 20 competent valves were analysed in the study. The material was collected during multiorgan retrievals. After harvesting, IScm long venous fragments were assessed with respect to valve presence. A 4-cm fragment with a valve was used for the analysis. Valve competence was assessed twice: after sampling and after 21 days of preservation. The valves were subjected to 136 cm water column pressure test. Denaturation in cold ischaemia consists of preservation of vessels at 4_C in a preservation medium containing antibiotics. Bacteriological and morphological examinations by light microscopy were performed. Results: After the preservation period, all the valves retained their mechanical properties. Well-preserved elastic elements of vascular wall were maintained in all vessels. Minor fragmentation of elastic fibres was observed and the structure of vascular wall was usually regular. Conclusions: Our study indicates that denaturation in cold ischaemia allows for the maintenance of the properties and physiological functions of the valves after preservation. This effect is related to the good condition of elastic fibres, venous wall structure and the valve itself.

Keywords: denaturated venous homograft, valvesof deep veins, Surgery, venous homografts


Most Viewed Current Articles

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

24 Aug 2021 : Review article  

Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives

DOI :10.12659/AOT.931664

Ann Transplant 2021; 26:e931664

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358