Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Key-note lecture: Twenty five years of bone marrow transplantation in Poland

W W Jędrzejczak

Ann Transplant 2009; 14(1): 17-18 :: ID: 880256


The first allogeneic bone marrow transplantation in Poland was performed in November, 28, 1984. Patient was 6 year old girl with Diamond-Blackfan anemia (inherited absence of red cells) following 60 transfusions with significant hemosiderosis conditioned with busulfan and cyclophosphamide. Donor was her 4-yr old HLA-identical sister. The entire technology was reinvented in Poland partially with help of published evidence and none of the team members has received training in that area abroad. Transplantation was successful and the patient is alive and well in 2009. It was also the 2nd successful transplantation in this disease in the world. The same team of Military School of Medicine in
Warsaw has performed in subsequent two years additional 8 allogeneic transplantations exclusively in patients with advanced diseases, has achieved engraftment in 6 cases and long term survival (ongoing) in 2 cases (one more with Diamond-Blackfan anemia and one with accelerated phase of chronic myelocytic leukemia). In 1985 the same team has performed the first autologous transplantation in a case of acute lymphoblastic leukemia. In 1987 team was dissolved by administrative decision but was able to publish detailed transplantation protocol that has allowed other Polish teams to continue this task. The next team has started activity in Wroclaw in 1989, followed by the teams in Poznan and Katowice in 1990 and 1991 respectively. This last team has performed the first allogeneic transplantation from unrelated donor in 1997. Currently, in Poland they are 17 active transplantation teams performing yearly approximately 800 transplantations including 500 autologous and 300 allogeneic, half of them from unrelated do- nors. As based on EBMT data the results of these transplantations are similar to transplantations performed in Western European Centers.

Keywords: Rational drug use, adverse drug effects( ADE), generic drugs, medication profile, Transplantation, Diamond-Blackfan anemia

Add Comment 0 Comments

In Press

12 Feb 2024 : Original article  

No Prognostic Impact of Graft-to-Recipient Weight Ratio on Hepatocellular Carcinoma Recurrence Following Li...

Ann Transplant In Press; DOI: 10.12659/AOT.942767  

21 Feb 2024 : Original article  

Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians

Ann Transplant In Press; DOI: 10.12659/AOT.943498  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358