Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Ethical consideration of living donor organ transplantation

A Tibell

Ann Transplant 2009; 14(1): 18-19 :: ID: 880263


The use of a live donor as a source for organs for transplantation is a unique act in medicine. With very few exceptions, the basis for medical treatment is the benefit for the individual patient. However, in the case of a live donor, we actually harm - or at least potentially harm - a healthy individual for the benefit of someone else. A free and truly informed consent is the basis for live donation. The potential donor must be capable of understanding the information given and the decision to donate should be voluntary and without coercion. The Amsterdam and Vancouver Fora on live donation establish the responsibility of the transplant team to perform complete medical and psychosocial evaluation and to care for the donor during post-operative recovery. There is also the responsibility to facilitate long-term follow-up and treatment and to identify and track complication. It is recommended that the donor should be evaluated by a different team than the one caring for the recipient. The scarcity of organs is a worldwide problem. No country has a true excess. Still, a global trade in organs has developed with transplant tourism and even trafficking of donors and organs. WHO has estimated that 50,000 kidneys are transplanted yearly worldwide. 20,000 of them are from live donors and the number of trafficked organs is estimated to be between 5,000 and 8,000 per year. A number of scientific gropus have performed psychosocial evaluation of paid donors and the results in Iran, Pakistan and the Philippines are similar. A majority of the donors regret donation and they feel that they have not recovered fully. In the absolute majority of cases, the economical situation one year after donation has not improved. It is important that all countries with transplantation activities have a regulatory framework for live and deceased donation. To lessen the burden on live donors it is likewise important to establish and promote deceased donation globally.

Add Comment 0 Comments

In Press

12 Feb 2024 : Original article  

No Prognostic Impact of Graft-to-Recipient Weight Ratio on Hepatocellular Carcinoma Recurrence Following Li...

Ann Transplant In Press; DOI: 10.12659/AOT.942767  

21 Feb 2024 : Original article  

Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians

Ann Transplant In Press; DOI: 10.12659/AOT.943498  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358