Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Evaluation of cadaveric donor usability for pancreas harvesting
and pancreatic islets transplantation in Poland

K Pawelec, J Czerwiński, A Berman, M Wszoła, P Fiedor

Ann Transplant 2009; 14(1): 21-21 :: ID: 880275

Abstract

Background: Donor shortage is a common problem among all transplant centres.  Frequently the acceptance criteria of pancreas for islets isolations are extended to marginal donors. Transplant success rate of islet isolations varies between centres and the ratio is 1/3 to 1/5. Donor status strongly influences islet yield. The clinical Islet Transplantation Programme started in 2008 in Poland, therefore we investigated the potential number of pancreases for islet isolation.
Material/Methods: We analyzed clinical data of 427 effective donors referred to Poltransplant in 2008. Age, ICU stay, treatment with vasoactive drug, hypotension, cardiac arrest, body mass index, glucose and amylase level, past history was analysed. For each variable we allocated points and for each donor total score was calculated (maximal score 75). Applied scoring system  was based on literature review and clinical experience.
Results: Of 427 effective donors: 20 (4.7%) became utilised pancreas donors for simultaneous pancreas-kidney procedure. 3 (0.7%) were used for islet isolation (with 1 clinical islet transplantation). Out of remaining 404 donors, 36 had high number of points in the applied score system (over 60) and could be potentially (basing on analysis of clinical risk factors) optimal pancreas donors for islets recovery.
Conclusions: The number of optimal donors that could be allocated for islet  isolation should cover the needs of the clinical Islet Transplant Programme.  The use of optimal donors should lead to maximize the number of transplantable islet isolations.

Add Comment 0 Comments

In Press

12 Feb 2024 : Original article  

No Prognostic Impact of Graft-to-Recipient Weight Ratio on Hepatocellular Carcinoma Recurrence Following Li...

Ann Transplant In Press; DOI: 10.12659/AOT.942767  

21 Feb 2024 : Original article  

Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians

Ann Transplant In Press; DOI: 10.12659/AOT.943498  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358