Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

The assessment of residual kidney function after living donor nephrectomy

M Bieniasz, A Kwiatkowski, P Domagała, J Gozdowska, R Kieszek, L Ostrowski, A Deptuła, J Trzebicki, M Durlik, L Pączek, A Chmura

Ann Transplant 2009; 14(1): 25-25 :: ID: 880289

Abstract

Background: The number of patients on the waiting list for kidney transplantation is increasing as a result of cadaveric donor's shortage. One of the ways to expand the donor pool is living donor transplantation. However, only 2-3% of kidney transplants in Poland are obtained from the living related donors. The aim of this study was to assess residual renal function and incidence of microalbuminuria in living kidney donors.
Material/Methods: Between 1995 and 2005, 66 living donor open nephrectomies
were performed. Physical examination, blood and urine tests and ultrasonography were performed prior to nephrectomy and at every follow-up visit (every 12 months post-op) in the donors. Donor mean age was 40.9 years (range 29-60). The donors were predominantly female (52.5%). 27 donors did not report for follow-up visits. Observation period ranged from 36 to 156 months.
Results: Mean creatinine concentration increased from 0.89 mg/dl prior to donation to 1.12 mg/dl and 1.1 mg/dl at 36 and 84 months post nephrectomy, respectively. Mean creatinine clearance according to the Cockroft-Gault formula decreased from 94.27 ml/min prior to donation to 80.2 ml/min and 72.2 ml/min at 36 and 84 months post donation, respectively. Microalbuminuria was observed in one patient (2.6%) at 84 months following nephrectomy.
Conclusions: Living kidney donation results in a reduced creatinine clearance in the donor. Follow-up of living kidney donors is essential in determining risk factors for deterioration of residual kidney function.

Keywords: Kidney Transplantation

Add Comment 0 Comments

In Press

Original article  

Steroid Use in ABO-Incompatible Kidney Transplants: Withdrawal vs Maintenance

Ann Transplant In Press; DOI: 10.12659/AOT.947747  

Original article  

Intra-Arterial Contrast-Enhanced Ultrasound for Transcatheter Thrombolysis in Post-Transplant Hepatic Arter...

Ann Transplant In Press; DOI: 10.12659/AOT.947500  

Original article  

Early Atropine Protocol Enhances Dobutamine Stress Echocardiography in End-Stage Liver Disease: A Practical...

Ann Transplant In Press; DOI: 10.12659/AOT.950166  

Most Viewed Current Articles

15 Aug 2023 : Review article   7,349

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation

DOI :10.12659/AOT.939750

Ann Transplant 2023; 28:e939750

03 Jan 2023 : Original article   7,212

Impact of Autologous Stem Cell Transplantation on Primary Central Nervous System Lymphoma in First-Line and...

DOI :10.12659/AOT.938467

Ann Transplant 2023; 28:e938467

16 May 2023 : Original article   7,034

Breaking Antimicrobial Resistance: High-Dose Amoxicillin with Clavulanic Acid for Urinary Tract Infections ...

DOI :10.12659/AOT.939258

Ann Transplant 2023; 28:e939258

28 May 2024 : Original article   6,633

Effect of Dexmedetomidine Combined with Remifentanil on Emergence Agitation During Awakening from Sevoflura...

DOI :10.12659/AOT.943281

Ann Transplant 2024; 29:e943281

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358