Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Liver regeneration in 120 consecutive living-related liver donors

K Zieniewicz, R Paluszkiewicz, P Kalinowski, P Hevelke, I Grzelak, R Pacho, M Krawczyk

Ann Transplant 2009; 14(1): 29-29 :: ID: 880305


Background: Living related liver transplantation for paediatric patients has
become an acceptable, low risk treatment option. The aim of this study was to assess the extent of the donor's liver regeneration.
Material/Methods: Between October 1999 and January 2008 120 living related donors were operated on and 109 grafts consisting of II, III segments and 11 grafts consisting of II, III and IV segments were harvested. Volumetric assessment of the donor's liver and selected segments was performed using computed tomography. After procurement every graft was weighed. Seven and 30 days, and 12 months after the operation donor's liver remnant was evaluated for differences in volume.
Results: Significant correlation between liver graft mass and its volume assessed with computed tomography was found (r=0.781; p<0.05). Twelve months after procurement average regeneration index was significantly higher in donors of segments II, III, IV (139.11±22.88%) versus donors of segments II and III  (108.83±17.25%) (p<0.05). Conclusions: Liver regeneration after procurement of selected liver segments from the living donors is a consistent finding and computed tomography is an accurate imaging modality to track changes in liver volume. This study shows positive correlation between the size of liver graft and regeneration of liver remnant in the donor

Keywords: Liver Transplantation, Living Donors, clinical outcome

Add Comment 0 Comments

In Press

Original article  

Implementation and Evaluation of Discharge Planning for Patients Undergoing Umbilical Cord Blood Transplant...

Ann Transplant In Press; DOI: 10.12659/AOT.943770  

Original article  

Long-Term Graft and Patient Survival After Re-Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.943903  

Original article  

Post-Donation Regret and Anxiety Among Family Living Liver Donors: The Mediating Roles of Family Relationsh...

Ann Transplant In Press; DOI: 10.12659/AOT.944176  

Original article  

Effect of the Organ Donation Quality System on Donation Activity of Warsaw Hospitals

Ann Transplant In Press; DOI: 10.12659/AOT.943520  

Most Viewed Current Articles

05 Apr 2022 : Original article   12,118

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article   8,587

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article   8,510

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report   6,430

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358