21 May 2009
Ann Transplant 2009; 14(1): 39-40 :: ID: 880341
Background: Charlson Co morbidity Index-Orthotopic LT (CCI-OLT) is a modified clinical score recently found to be useful in the assessment of a long term survival after liver transplantation (LTx) (Volk et al. Liver Transplantation 2007). It includes 9 most important associated conditions selected in multivariate analysis on a large cohort of transplanted patients. Its role in predicting early mortality after LTx has not yet been investigated. Aim: Evaluation of CCI-OLT as a potential predictor of one-month mortality after LTx.
Material/Methods: A group of 169 consecutive patients (103 males and 67 females, median age in both groups 51 years) who received their elective LTx at our centre was analysed. Patients transplanted for fulminant hepatic failure were excluded from the analysis. Viral (39%) and alcohol induced (23%) cirrhosis were most common indications for LTx. CCI-OLT index was assessed in all patients. Statistical analysis was performed with StatView Program.
Results: 146 (86%) subjects survived and 23 (14%) died within 1 month after
LTx. Fifty one (30%) patients suffered from at least 1 co-morbidity included in CCI-OLT index, a number significantly lower than in population studied by Volk et al. Direct comparison of the groups of survivors and non-survivors showed no significant difference in terms of the total frequency of co-morbidities (30.1% vs. 30.4%, p>0.99), their number and type. The most common associated condition in both groups was diabetes mellitus.
Conclusions: Contrary to the long term survival, CCI-OLT does not seem to have a role as a predictor of early (one-month) mortality after LTx.
Keywords: Liver Transplantation
04 Aug 2022 : Original articleLong-Term Patency of All-in-One Sleeve Patch Graft Venoplasty in 16 Patients Who Underwent Living Donor Liv...
Ann Transplant In Press; DOI: 10.12659/AOT.936888
22 Jul 2022 : Original articleDiagnostic Role of Tumor Markers for Hepatocellular Carcinoma in Liver Transplantation Candidates: An Analy...
Ann Transplant In Press; DOI: 10.12659/AOT.936937
22 Jul 2022 : Original articleDevelopment of a Novel Model for Predicting Postoperative Short-Term Outcome in Patients with Hepatitis B-R...
Ann Transplant In Press; DOI: 10.12659/AOT.936732
Most Viewed Current Articles
26 Jan 2022 : Review articleRecurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models
Ann Transplant 2022; 27:e934924
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
24 Jul 2020 : Review articleKidney Transplantation in the Times of COVID-19 – A Literature Review
Ann Transplant 2020; 25:e925755