21 May 2009
Causes of liver disqualification in cadaveric donor population in department of general transplant and liver surgery of Medical University of Warsaw (2003–2008)
M Urban, R Stankiewicz, M Galas, B CieślakAnn Transplant 2009; 14(1): 42-42 :: ID: 880351
Abstract
Background: Increasing number of transplantations in Poland shows the growing problem of organ shortage. It is connected not only with unsatisfactory number of donors, but also with remarkable amount of rejected grafts.
Material/Methods: We retrospectively analyzed information about 798 potential deceased liver donors referred to the department's coordinator from 2003 to
2008. 537 liver transplantations were performed, which was 67% of the total number of organ donor notifications. Disqualification rate ranged from 44% in 2003 to 24% in the last year. According to the time of disqualification during coordinating procedure we classified causes of retrieval into three groups: 1) donor's disqualification - before organ harvesting (based on abnormal biochemical blood tests' results, hemodynamic donor condition or risk of neoplasmatic process); 2) intraoperative disqualification (e.g. suspicion of abdominal malignant tumour or macroscopic liver evaluation); 3) organ disqualification - based on histopathological examination.
Results: During analyzed period 261 donors out of 798 donor notifications were disqualified, which stated 33%. The first of above group was the greatest. Before harvesting 65% (n=171) livers were excluded from the transplantation. After intraoperative evaluation 19% (n= 49) of livers were rejected, while histopathological results disqualified 16% (n=41) of grafts.
Conclusions: Organ enrolment is based on multistage qualifying process.
Decreasing number of disqualifications is probably connected with extending donor criteria and better education among medical teams recruiting potential cadaveric donors.
Keywords: Deceased Donor, Liver Transplantation, Organ Procurement
In Press
Original article
Common Versus External Iliac Arterial Anastomosis in Kidney Transplantation: A Bicentric Retrospective Anal...Ann Transplant In Press; DOI: 10.12659/AOT.953269
Original article
Protective Effects of Quercetin and Sucrose on Cold Preservation Injury in Porcine Kidneys Donated After Ca...Ann Transplant In Press; DOI: 10.12659/AOT.952503
Original article
Four Years of Clinical Experience With COVID-19 Outcomes in Heart Transplant RecipientsAnn Transplant In Press; DOI: 10.12659/AOT.952888
Original article
Determinants of Lack of Consent for Deceased Organ Donation Among Nurses and Physicians: A Cross-Sectional ...Ann Transplant In Press; DOI: 10.12659/AOT.953598
Most Viewed Current Articles
24 Aug 2021 : Review article 21,160
Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future PerspectivesDOI :10.12659/AOT.931664
Ann Transplant 2021; 26:e931664
29 Dec 2021 : Original article 17,335
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
22 Nov 2022 : Original article 16,325
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
05 Apr 2022 : Original article 16,249
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604






