21 May 2009
Inadequate blood pressure control in vast majority of kidney allograft recipients and patients with coronary artery disease with and without comorbidities
J Malyszko, J Malyszko, H Bachorzewska-Gajewska, B Poniatowski, S Dobrzycki, M MysliwiecAnn Transplant 2009; 14(1): 49-49 :: ID: 880377
Abstract
Target blood pressure according to ESH/ESC guidelines should be lower
than 140/90 mm Hg in general population, while in patients with chronic
kidney disease-CKD or diabetes lower than 130/80 mm Hg. Hypertension is widely accepted risk factor for coronary artery disease, chronic heart failure or CKD. In kidney transplant recipient-Tx, prevalence of hypertension is 60-80%. The aim of the study was to assess the prevalence of achieved target blood pressure in 525 patients with coronary artery disease-CAD and 150 prevalent Tx. In CAD population 30% had diabetes and 33% had CKD. In 52% of the patients diabetes and/or CKD was diagnosed, in Tx population 15% had diabetes. Hypertension was diagnosed and treated in 72% in CAD and 90% in Tx. In CAD population without diabetes and CKD only 47% achieved target blood pressure, while in the population with CKD/and/or diabetes only 31%. Patients were treated with ACEi (72%), CCB (28%), diuretics (27%) and b-blockers (89%). In Tx more than 60% required 3 and more hypotensives. Only 40% Tx achieved target BP. In Tx most commonly used hypotensives were CCB (84%), b-blockers (68%), diuretics (51%), ACEi (38%), a-blockers (15%). Despite polytherapy the optimal blood pressure control was not achieved in majority of patients. CAD and Tx had a high prevalence of hypertension, thus they should be treated adequately. More efforts should be put to optimizing blood pressure control, particularly when other co-morbidities are present. Wide use of b-blockers and ACEi under using in Tx population should be noted.
Keywords: Kidney Transplantation
In Press
Original article
A New Routine Immunity Score (RIS2020) to Predict Severe Infection in Solid-Organ Transplant RecipientsAnn Transplant In Press; DOI: 10.12659/AOT.946233
Original article
Survival Analysis of Liver Transplants in Patients with Acute Liver Failure from Acetaminophen and Mushroom...Ann Transplant In Press; DOI: 10.12659/AOT.946485
Original article
Medication Adherence Among Pediatric Post-Heart Transplant Patients in a Tertiary Care HospitalAnn Transplant In Press; DOI: 10.12659/AOT.946905
Most Viewed Current Articles
03 Jan 2023 : Original article 6,377
Impact of Autologous Stem Cell Transplantation on Primary Central Nervous System Lymphoma in First-Line and...DOI :10.12659/AOT.938467
Ann Transplant 2023; 28:e938467
16 May 2023 : Original article 6,038
Breaking Antimicrobial Resistance: High-Dose Amoxicillin with Clavulanic Acid for Urinary Tract Infections ...DOI :10.12659/AOT.939258
Ann Transplant 2023; 28:e939258
15 Aug 2023 : Review article 5,925
Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ TransplantationDOI :10.12659/AOT.939750
Ann Transplant 2023; 28:e939750
17 Jan 2023 : Original article 5,156
Non-Cryopreserved Peripheral Blood Stem Cell Graft for Autologous Hematopoietic Stem Cell Transplantation i...DOI :10.12659/AOT.938595
Ann Transplant 2023; 28:e938595