Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Evaluation differents immunosuppressive protocols in patients after kidney transplantation

L Zair, T Sulikowski, M Kamiński, Z Ziętek, S Zeair, A Sierocka, K Tejchman, M Wiśniowski, M Szałata, K Kłoda, M Ostrowski

Ann Transplant 2009; 14(1): 51-51 :: ID: 880386


Prevention and control of renal allograft rejection have been some of the main problems since the first kidney transplant. Common use of selective immunosuppressive agents became an effective and safe way of treatment Nevertheless comparing immunosuppressive protocols containing different
types of drugs is still a pivotal aim of many studies. Here we are presenting the experience from two different centres in Szczecin.The aim of our study was to compare two immunosuppressive protocols: Tac MMF steroids with Cs Aza steroids and their efficacy, incidence of acute rejection, side effects, incidence of IGF, DGF and serum creatinine concentrations after 1 month and 1 year. We have investigated medical records of 1248 patients, treated between the years 1990-2007 in two different centres in Szczecin. 553 patients were selected and divided into two groups - Tac MMF steroids protocol recipients (n=135) and Cs Aza steroids protocol recipients (n=418). We observed higher incidence of IGF with Tac MMF steroids protocol use, and higher incidence of DGF with Cs Aza steroids protocol use. There were no significant differences between immunosuppressive protocols and patients gender in regard to episodes of acute rejection. The incidence of acute rejection was higher in younger patients. Side effects after immunosuppressive treatment were more common in Tac MMF steroids protocol recipients and in younger patients. There were no significant differences between the serum creatinine concentrations after 1 month and 1 year in regard to both of the protocols.

Keywords: Immunosuppression, Kidney Transplantation

Add Comment 0 Comments

In Press

12 Feb 2024 : Original article  

No Prognostic Impact of Graft-to-Recipient Weight Ratio on Hepatocellular Carcinoma Recurrence Following Li...

Ann Transplant In Press; DOI: 10.12659/AOT.942767  

21 Feb 2024 : Original article  

Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians

Ann Transplant In Press; DOI: 10.12659/AOT.943498  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358