Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Long term acid-base balance disorders during kidney transplantation

K Tejchman, L Domański, T Sulikowski, M Kamiński, J Sieńko, M Romanowski, M Ostrowski

Ann Transplant 2009; 14(1): 53-54 :: ID: 880395


Reperfusion of transplanted kidney is connected with many metabolic changes which are the result of the kidney's initial condition and preservation. These alterations are the part of ischemia-reperfusion injury with acid-base balance disorders as one of them. The study's purpose was the analysis of its influence on the kidney function during 24 months after transplantation. The examined group consisted of 86 recipients. Measurements had been made 9 times - 0, 1, 3, 5, 10, 15, 20, 25, 30 minutes after unclamping renal vessels including: blood sample for gas analysis, expiratory pCO[sub]2[/sub], tidal volume and respiratory rate. The evaluation of temporary acid-base balance state was made on the basis of common parameters: pH, pCO[sub]2[/sub], [HCO[sub]3[/sub]-], BE. Examined patients were in general anaesthesia with stable external conditions (O2 saturation, heart rate, blood pressure, temperature). Blood samples were analyzed using Corning 278 and 248 blood gas analyzer; vital parameters were recorded using Ohmeda 5250 RGM and Dräger Sulla 909V / Julian apparatus. The analysis has shown increasing metabolic acidosis during reperfusion. Disorders are dependent from HLA-DR matching, donor's gender and have influence on early creatinine concentrations after operation. Analysis showed also influence on a long term kidney function parameters.

Keywords: Ischemia reperfusion injury, Kidney Transplantation

Add Comment 0 Comments

166 0

In Press

02 Jun 2023 : Original article  

Survival analysis of transplant-associated thrombotic microangiopathy under different diagnostic criteria a...

Ann Transplant In Press; DOI: 10.12659/AOT.939890  

17 May 2023 : Original article  

Results of Liver Retransplantation After Rescue Hepatectomy: A Single-Center Study

Ann Transplant In Press; DOI: 10.12659/AOT.939557  

10 May 2023 : Original article  

Incidence of Thromboembolic Complications Following Kidney Transplantation with Short and Extended Aspirin ...

Ann Transplant In Press; DOI: 10.12659/AOT.939143  

Most Viewed Current Articles

24 Aug 2021 : Review article  

Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives

DOI :10.12659/AOT.931664

Ann Transplant 2021; 26:e931664

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358