21 May 2009
Is there a relationship between coronary artery calcification and serum calcium, phosphorus, pth levels and calcium-phosphorus product in renal transplant recipients ?
Z Serafïn, P Stróżecki, A Adamowicz, P Przygoński, G Dymek, Z Włodarczyk, J Manitius, W LasekAnn Transplant 2009; 14(1): 59-59 :: ID: 880414
Abstract
Background: Coronary artery calcification (CAC) is present in about 2/3 of
patients starting dialysis therapy. Serum calcium (Ca), phosphorus (P), parathormone (PTH) levels and calcium-phosphorus product (CaxP) are acknowledged factors of vascular calcifications in patients with chronic kidney disease (CKD). CAC is associated with increase of mortality in patients with
CKD. The aim of the study was to evaluate relationship between CAC and Ca, P, PTH levels and CaxP in renal transplant recipients (RTR).
Material/Methods: The study group consisted of 104 RTR (31 females and 73 males), aged 49±12 years. All patients received a graft from the deceased donors. CAC was determined with multi-detector row computed tomography as a total calcium score (CS) and calcium mass (CM). Serum Ca, P, PTH and CaxP product were analysed. Duration of renal replacement therapy was also
analysed. Glomerular fi ltration rate was calculated with abbreviated MDRD
equation (eGFR). Results are shown as mean ±SD in Table.
Results: CAC was found in 72 patients (69%). We compared RTR without CAC and those with CAC. No correlation was found between either CS and CM and: Ca, P, CaxP and PTH in the whole analysed group or in CAC+ group.
Conclusions: The prevalence of CAC in RTR is similar to that observed in patients beginning dialysis therapy. No relationship was found between serum Ca, P, PTH, CaxP product and CAC. These results may suggest that CAC occurs before beginning RTR.
Keywords: Kidney Transplantation, clinical outcome, Transplantation
In Press
Original article
Diagnostic Utility of FAR1 Methylation Levels in Hepatocellular Carcinoma Patients Undergoing Liver Transpl...Ann Transplant In Press; DOI: 10.12659/AOT.951568
Original article
Inferior Long-Term Outcome of Fatty Liver Allografts After Orthotopic Liver TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.950589
Database Analysis
Identification and Validation of Liver Transplantation-Induced Acute Lung Injury Biomarkers Using a Bioinfo...Ann Transplant In Press; DOI: 10.12659/AOT.950289
Original article
Survival and Recurrence in Liver Transplant Patients With Intrahepatic Cholangiocarcinoma and Hepatocellula...Ann Transplant In Press; DOI: 10.12659/AOT.950997
Most Viewed Current Articles
24 Aug 2021 : Review article 18,372
Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future PerspectivesDOI :10.12659/AOT.931664
Ann Transplant 2021; 26:e931664
05 Apr 2022 : Original article 14,731
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
22 Nov 2022 : Original article 14,244
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
29 Dec 2021 : Original article 13,752
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588






