21 May 2009
The occurrence of mood disorders in patients after heart transplantation
R Pudlo, M Piegza, M Zakliczyński, M ZembalaAnn Transplant 2009; 14(1): 63-63 :: ID: 880429
Abstract
Background: Mood disorders are considered as a common and troublesome
complication after heart transplantation. However, there is no agreement as to reasons for their higher incidence risk and prophylaxis methods. To date, various studies have yielded contradictory results.
Material/Methods: 49 heart transplant recipients have been evaluated during the first 16 weeks after OHT. Using the ICD-10 criteria, the incidence of mood disorders and 17 demographic and medical factors potentially influencing the probability of a depressive and hypomanic syndrome were studied.
Results: 3 manic or hypomanic episodes, 12 cases of mild mood elevation and 27 depression episodes have been observed. No correlation has been revealed between the occurrence of the episode of a hypomanic syndrome and each of the studied factors. We found that the risk of a depression syndrome is higher in patients, who experienced a greater number of "false alarms" (the number of requests to arrive to the medical centre not finished with transplantation), and in patients with longer hospitalization period. Analysing moderate depressive episodes we proved that their occurrence probability is also higher as a result of underlying diseases and lower mean cyclosporine level.
Conclusions: Depression episodes are a frequent phenomenon during early post-OHT rehabilitation. "False alarms", older age, long-lasting hospitalizations and low cyclosporine level increase the risk of post-OHT depression. Manic episodes occur sporadically after OHT.
Keywords: Heart Transplantation
In Press
08 Mar 2024 : Original article
Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...Ann Transplant In Press; DOI: 10.12659/AOT.943532
14 Mar 2024 : Original article
Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort StudyAnn Transplant In Press; DOI: 10.12659/AOT.943652
14 Mar 2024 : Case report
Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...Ann Transplant In Press; DOI: 10.12659/AOT.942358
15 Mar 2024 : Review article
Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...Ann Transplant In Press; DOI: 10.12659/AOT.941185
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860