Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Effect of fungal infections in diabetic patients after simultaneous pancreas-kidney transplantation

E Swoboda-Kopeć, I Netsvyetayeva, A Kwiatkowski, L Pączek, G Młynarczyk, M Łuczak, M Jaworska-Zaremba, M Sikora, S Błachnio, P Fiedor

Ann Transplant 2009; 14(1): 72-72 :: ID: 880465


Material/Methods: 40 insulin-dependent diabetic patients as recipients were
analysed. The observation period lasted between 2 months to 12 years. The
clinical material was obtained from urea and blood samples as well as drains
samples from infected tissues.
Results: The satisfactory graft function of both transplanted organs was observed in 31 patients. The pancreas grafts were rejected in 8 recipients due to the early post-transplant complications. Out of this number, two cases were associated with Candida fungal infections: necrotic pancreatitis of the grafted organ and infection of haematoma in the pancreatic graft region. Two cases of death occurred during the observation period, but no connection with transplant surgical procedures was stated.Fungal infections were observed in 5 patients in the early period after transplantation (up to 1 month). The majority of infections was associated with the urinary system - 3. The remained infections occurred at the operated sites - 4 cases.During the intermediate period of observation (2-6 months) only one case of fungal infection was found: urinary tract mixed infection.
Fungal infections were observed in 7 patients in the late period of observation. Urinary tract infections occurred in 3 cases, digestive tract infections in 2 cases and oesophagus contamination in one case. Additionally, oral cavity mycosis was found in one case of studied patients.
Conclusions: Our clinical data strongly indicate that fungal infections may play a key role as a risk factor which takes responsibility for the loss of pancreas allografts. Early prevention and /or treatment of fungal infections can protect pancreas in SPKTx recipients from the rejection process. Satisfactory kidney graft function in all Pts was observed.

Keywords: fungal infections

Add Comment 0 Comments

In Press

06 Feb 2024 : Case report  

Successful Sequential Liver and Isolated Intestine Transplantation for Mitochondrial Neurogastrointestinal ...

Ann Transplant In Press; DOI: 10.12659/AOT.941881  

12 Feb 2024 : Original article  

No Prognostic Impact of Graft-to-Recipient Weight Ratio on Hepatocellular Carcinoma Recurrence Following Li...

Ann Transplant In Press; DOI: 10.12659/AOT.942767  

21 Feb 2024 : Original article  

Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians

Ann Transplant In Press; DOI: 10.12659/AOT.943498  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358