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30 June 2011

Acute kidney injury after procedures of orthotopic liver transplantation

Lidia Lewandowska, Joanna Matuszkiewicz-Rowinska

Ann Transplant 2011; 16(2): 103-108 :: ID: 881872

Abstract

The incidence of acute kidney injury (AKI) after orthotopic liver transplantation (OLT) ranges from 40 to 70%, with 8–17% of these patients requiring renal replacement therapy. The aetiology of this syndrome is multi-factorial, and its most common cause is ischaemia in the early postoperative period, and toxicity of immunosuppressive drugs and infectious complications at long term. AKI significantly increases the risk of death and development of chronic renal failure in the late post-OLT period. We discussed in short in our work the risk factors of AKI, diagnostics and clinical management in this group of patients.

Keywords: Liver Transplantation, hepato-renal syndrome, Dialysis, calcineurin inhibitors

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358