03 February 2014 : Case report
Candida albicans arteritis transmitted by preservation fluid after liver transplantation
Pietro AddeoABCDEFG, Anne-Catherine SaouliABCE, Marie Lorraine Woehl-JaegleCDF, Bernard ElleroBDF, Elie OussoultzoglouBCF, Luc MarcellinBDF, Philippe BachellierABCDEFGDOI: 10.12659/AOT.889831
Ann Transplant 2014; 19:64-67
Abstract
Background: Fungal infections remain among the main causes of mortality in the chronically immunosuppressed liver transplant (LT) patient. Bacterial and fungal contamination of preservation fluid (PF), in which grafts are stored, represents a potential source of infection for recipients.
Case Report: A 54-year-old patient underwent LT for chronic alcoholic cirrhosis. Mycological culture of the liver PF was positive for Candida albicans. The patient received antimycotic prophylaxis for 4 weeks in absence of clinical and serological signs of infection. He was urgently readmitted 4 months later with hemobilia caused by an arterial pseudoaneurysm that was fistulized in the biliary anastomosis. After an unsuccessful embolization, arterial resection and reconstruction and a biliodigestive anastomosis were performed, with an uneventful postoperative course. Pathology found a mycotic arteritis of the graft artery. Mycotic culture of the arterial segment confirmed the presence of the same Candida albicans genotype previously isolated in the PF.
Conclusions: Mycotic arteritis is one of the possible complications of yeast contamination of PF. Surgeons and physicians involved in the care of LT patients should be aware of this potentially lethal complication and adopt all the available means for early detection.
Keywords: Hemobilia, arterial rupture, Mycotic aneurysms, Candida albicans, preservation fluid, Liver Transplantation
In Press
Original article
Common Versus External Iliac Arterial Anastomosis in Kidney Transplantation: A Bicentric Retrospective Anal...Ann Transplant In Press; DOI: 10.12659/AOT.953269
Original article
Protective Effects of Quercetin and Sucrose on Cold Preservation Injury in Porcine Kidneys Donated After Ca...Ann Transplant In Press; DOI: 10.12659/AOT.952503
Original article
Four Years of Clinical Experience With COVID-19 Outcomes in Heart Transplant RecipientsAnn Transplant In Press; DOI: 10.12659/AOT.952888
Original article
Determinants of Lack of Consent for Deceased Organ Donation Among Nurses and Physicians: A Cross-Sectional ...Ann Transplant In Press; DOI: 10.12659/AOT.953598
Most Viewed Current Articles
24 Aug 2021 : Review article 21,160
Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future PerspectivesDOI :10.12659/AOT.931664
Ann Transplant 2021; 26:e931664
29 Dec 2021 : Original article 17,335
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
22 Nov 2022 : Original article 16,325
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
05 Apr 2022 : Original article 16,249
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604






