03 November 2014 : Original article
Comparative Analysis of Hypertension and its Causes among Renal Replacement Therapy Patients
Łukasz CzyżewskiABCDEF, Joanna Sańko-ResmerABD, Janusz WyzgałADE, Andrzej KurowskiCDDOI: 10.12659/AOT.891248
Ann Transplant 2014; 19:556-568
Abstract
BACKGROUND: In renal replacement therapy (RRT) patients, the target values of blood pressure (BP) are being continuously modified and excessive fat tissue may even have a protective impact on the risk of mortality due to cardiovascular causes – the “obesity paradox”. The purpose of the study was to compare the occurrence of hypertension (HTN) and its underlying causes in patients in the first year after kidney transplantation (KTx), and hemodialysis (HD) or peritoneal dialysis (PD) patients.
MATERIAL AND METHODS: A group of 120 RRT patients (PD, n=30; HD, n=40; KTx, n=50) was analyzed. The following research tools were used: (1) 24- or 44-h ambulatory blood pressure monitoring (ABPM); (2) bioelectrical impedance analysis (BIA); (3) traditional method – office BP; (4) Morisky-Green test; and (5) disease history. The significance level was p<0.05.
RESULTS: The analysis revealed (HTN) (on the basis of ABPM values and anti-hypertensive treatment) in 90% of PD patients, 83% of HD patients in the first 24 h after hemodialysis, and in 95% of HD patients in the second 24 h after hemodialysis. In patients in the 12th month after KTx, BP values went up along with increased creatinine and hemoglobin concentration and urine protein presence (r=0.38; r=0.31; r=0.38; p<0.05). HD had a statistically significant impact of fat tissue growth on reducing BP (r=–0.34; p<0.05).
CONCLUSIONS: Fat tissues play a cardioprotective role in the development of hypertension in HD patients. This shows the possibility of early noninvasive identification of patients exposed to development of chronic allograft nephropathy.
Keywords: Blood Pressure Monitoring, Ambulatory, Electric Impedance, Hypertension, Kidney Transplantation, Peritoneal Dialysis, Renal Dialysis
In Press
08 Mar 2024 : Original article
Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...Ann Transplant In Press; DOI: 10.12659/AOT.943532
14 Mar 2024 : Original article
Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort StudyAnn Transplant In Press; DOI: 10.12659/AOT.943652
14 Mar 2024 : Case report
Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...Ann Transplant In Press; DOI: 10.12659/AOT.942358
15 Mar 2024 : Review article
Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...Ann Transplant In Press; DOI: 10.12659/AOT.941185
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860