Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

03 November 2014 : Original article  

Comparative Analysis of Hypertension and its Causes among Renal Replacement Therapy Patients

Łukasz CzyżewskiABCDEF, Joanna Sańko-ResmerABD, Janusz WyzgałADE, Andrzej KurowskiCD

DOI: 10.12659/AOT.891248

Ann Transplant 2014; 19:556-568

Abstract

BACKGROUND: In renal replacement therapy (RRT) patients, the target values of blood pressure (BP) are being continuously modified and excessive fat tissue may even have a protective impact on the risk of mortality due to cardiovascular causes – the “obesity paradox”. The purpose of the study was to compare the occurrence of hypertension (HTN) and its underlying causes in patients in the first year after kidney transplantation (KTx), and hemodialysis (HD) or peritoneal dialysis (PD) patients.

MATERIAL AND METHODS: A group of 120 RRT patients (PD, n=30; HD, n=40; KTx, n=50) was analyzed. The following research tools were used: (1) 24- or 44-h ambulatory blood pressure monitoring (ABPM); (2) bioelectrical impedance analysis (BIA); (3) traditional method – office BP; (4) Morisky-Green test; and (5) disease history. The significance level was p<0.05.

RESULTS: The analysis revealed (HTN) (on the basis of ABPM values and anti-hypertensive treatment) in 90% of PD patients, 83% of HD patients in the first 24 h after hemodialysis, and in 95% of HD patients in the second 24 h after hemodialysis. In patients in the 12th month after KTx, BP values went up along with increased creatinine and hemoglobin concentration and urine protein presence (r=0.38; r=0.31; r=0.38; p<0.05). HD had a statistically significant impact of fat tissue growth on reducing BP (r=–0.34; p<0.05).

CONCLUSIONS: Fat tissues play a cardioprotective role in the development of hypertension in HD patients. This shows the possibility of early noninvasive identification of patients exposed to development of chronic allograft nephropathy.

Keywords: Blood Pressure Monitoring, Ambulatory, Electric Impedance, Hypertension, Kidney Transplantation, Peritoneal Dialysis, Renal Dialysis

Add Comment 0 Comments

742 8

In Press

10 Nov 2023 : Original article  

Effects of Preservation of Donor Liver Gastroduodenal Artery on Post-Transplant Biliary Complications in 18...

Ann Transplant In Press; DOI: 10.12659/AOT.941699  

07 Nov 2023 : Original article  

Allogeneic Hematopoietic Stem Cell Transplantation Can Improve Prognosis of Extramedullary Infiltration Pos...

Ann Transplant In Press; DOI: 10.12659/AOT.942197  

06 Nov 2023 : Original article  

Clinical Outcomes of Administration of Rituximab for Desensitization in Liver Transplant Patients with Pref...

Ann Transplant In Press; DOI: 10.12659/AOT.941456  

06 Nov 2023 : Original article  

Short-Term Monitoring of Graft Regeneration in Partial Liver Transplantation Recipients

Ann Transplant In Press; DOI: 10.12659/AOT.941444  

Most Viewed Current Articles

24 Aug 2021 : Review article  

Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives

DOI :10.12659/AOT.931664

Ann Transplant 2021; 26:e931664

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358