03 November 2014 : Original article
Comparative Analysis of Hypertension and its Causes among Renal Replacement Therapy PatientsŁukasz CzyżewskiABCDEF, Joanna Sańko-ResmerABD, Janusz WyzgałADE, Andrzej KurowskiCD
Ann Transplant 2014; 19:556-568
BACKGROUND: In renal replacement therapy (RRT) patients, the target values of blood pressure (BP) are being continuously modified and excessive fat tissue may even have a protective impact on the risk of mortality due to cardiovascular causes – the “obesity paradox”. The purpose of the study was to compare the occurrence of hypertension (HTN) and its underlying causes in patients in the first year after kidney transplantation (KTx), and hemodialysis (HD) or peritoneal dialysis (PD) patients.
MATERIAL AND METHODS: A group of 120 RRT patients (PD, n=30; HD, n=40; KTx, n=50) was analyzed. The following research tools were used: (1) 24- or 44-h ambulatory blood pressure monitoring (ABPM); (2) bioelectrical impedance analysis (BIA); (3) traditional method – office BP; (4) Morisky-Green test; and (5) disease history. The significance level was p<0.05.
RESULTS: The analysis revealed (HTN) (on the basis of ABPM values and anti-hypertensive treatment) in 90% of PD patients, 83% of HD patients in the first 24 h after hemodialysis, and in 95% of HD patients in the second 24 h after hemodialysis. In patients in the 12th month after KTx, BP values went up along with increased creatinine and hemoglobin concentration and urine protein presence (r=0.38; r=0.31; r=0.38; p<0.05). HD had a statistically significant impact of fat tissue growth on reducing BP (r=–0.34; p<0.05).
CONCLUSIONS: Fat tissues play a cardioprotective role in the development of hypertension in HD patients. This shows the possibility of early noninvasive identification of patients exposed to development of chronic allograft nephropathy.
Keywords: Blood Pressure Monitoring, Ambulatory, Electric Impedance, Hypertension, Kidney Transplantation, Peritoneal Dialysis, Renal Dialysis
17 May 2023 : Original articleResults of Liver Retransplantation After Rescue Hepatectomy: A Single-Center Study
Ann Transplant In Press; DOI: 10.12659/AOT.939557
10 May 2023 : Original articleIncidence of Thromboembolic Complications Following Kidney Transplantation with Short and Extended Aspirin ...
Ann Transplant In Press; DOI: 10.12659/AOT.939143
Most Viewed Current Articles
24 Aug 2021 : Review articleNormothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives
Ann Transplant 2021; 26:e931664
26 Jan 2022 : Review articleRecurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models
Ann Transplant 2022; 27:e934924
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
15 Mar 2022 : Case reportCombined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...
Ann Transplant 2022; 27:e935860