22 December 2014 : Original article
Fungal Infections in Liver Transplant Patients Admitted to the Intensive Care UnitRaghda MarzabanAE, Maged SalahD, Ahmed M. MukhtarF, Reham A. DwedarC, Walaa Abdel-LatifC, Ihab MahmoudB
Ann Transplant 2014; 19:667-673
BACKGROUND: Fungal infections have a significant impact on patient survival after liver transplantation, mostly caused by Candida and Aspergillus. The clinical manifestations vary, and range from colonization, active local infection, to severe invasive form. A high degree of suspicion is required for the early diagnosis and, accordingly, the optimal management of these infections. This study aimed to evaluate fungal infection in the Intensive care Unit (ICU) in admitted liver transplant patients, focussing of etiologic agent, clinical/laboratory presentation (including mortality), and risk factors.
MATERIAL AND METHODS: This retrospective study included living related liver transplanted patients admitted to the ICU. Clinical data was collected, thorough clinical evaluation was done, and laboratory tests were performed. Microbiological examination detecting the presence of fungus in various samples, using cultures and serology, and imaging investigations were carried out in all patients.
RESULTS: This study included 23 cases of ICU-admitted liver transplant patients who were diagnosed with fungal infection. Candida was the most common fungal infection and occurred at a mean of 2 months after transplantation; while Aspergillus was less common and occurred later with worse laboratory findings. Invasive fungal infection constituted 43% of the diagnosed cases. Difference in mortality between Aspergillus and Candida was insignificant, as was difference between patients with and without fungal infection.
CONCLUSIONS: Fungal infection among LT patients was common, including the invasive forms.
Keywords: Aspergillosis, Candida, Liver Transplantation
06 December 2022 : Original articleChanges in Physical Activity Due to Fear of COVID-19 and Its Impact on Depression Among Post-Liver Transpla...
Ann Transplant 2022; 27:e938239
04 October 2022 : Original articleIncidence of COVID-19 and Identification of Possible Risk Factors Associated with COVID-19 in Acute Renal T...
Ann Transplant 2022; 27:e937688
12 April 2022 : Letter/CorrespondencePancreas Allograft Thrombosis as a Post-COVID-19 Complication in a Diabetic Patient After Pancreas Transpla...
Ann Transplant 2022; 27:e935863
12 November 2021 : Original articleCoronavirus Disease 2019 (COVID-19) in Solid Organ Transplant Recipients: A Case-Control Study
Ann Transplant 2021; 26:e933152
17 Mar 2023 : Original articleConverting from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Patients with Hepatitis B Followi...
Ann Transplant In Press; DOI: 10.12659/AOT.938731
17 Mar 2023 : Original articleLevels of Procollagen Type I C-Terminal Pro-Peptide and Galectin-3, Arterial Stiffness Measured By Pulse Wa...
Ann Transplant In Press; DOI: 10.12659/AOT.938137
08 Mar 2023 : Original articlePostoperative Outcomes in 415 Patients Following Liver Transplantation Using Extended Donor Criteria: A Stu...
Ann Transplant In Press; DOI: 10.12659/AOT.939060
08 Mar 2023 : Original articleEvaluation and Use of Organs from Donors Poisoned by Organophosphorus Pesticide
Ann Transplant In Press; DOI: 10.12659/AOT.939343
Most Viewed Current Articles
24 Aug 2021 : Review articleNormothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives
Ann Transplant 2021; 26:e931664
26 Jan 2022 : Review articleRecurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models
Ann Transplant 2022; 27:e934924
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
15 Mar 2022 : Case reportCombined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...
Ann Transplant 2022; 27:e935860