Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

24 September 2015 : Original article  

Sodium Excretion Pattern at 1 Year After Kidney Transplantation and High Blood Pressure

Emilio RodrigoABCDEFG, Elena MonfáABCDEF, Zoila AlbinesDE, Mara SerranoDE, Gema Fernandez-FresnedoADE, Juan Carlos RuizDE, Celestino PiñeraDE, Rosa PalomarDE, Luis Martín-PenagosDE, Manuel AriasADEFG

DOI: 10.12659/AOT.893862

Ann Transplant 2015; 20:569-575

Abstract

BACKGROUND: High blood pressure (BP) after kidney transplantation decreases graft and patient survival. There is a causal relationship between high salt intake and increased BP in the general population, but the role of salt intake on post-transplant hypertension remains controversial. The aims of our study were to determine the pattern of salt intake in the first year post-transplantation and its influence on BP in our kidney transplant population.

MATERIAL AND METHODS: We selected 270 deceased-donor kidney transplant recipients with graft survival longer than 1 year and at least 1 adequate 24-h urinary sodium excretion measurement at the first year visit in order to be included in the analysis.

RESULTS: Some 87.0% patients had a sodium excretion (mean 165±73 mmol/day) higher than recommended. Male and younger recipients with a high body mass index had a higher sodium excretion. Among other variables, sodium excretion was independently related to higher systolic (b 3.529 per 100 mmol/day, 95%CI 0.725–6.334, p=0.014) and diastolic (b 1.866 per 100 mmol/day, 95%CI 0.237–3.496, p=0.025) BP.

CONCLUSIONS: A high percentage of kidney transplant recipients have salt intake higher than recommended, contributing to increased BP. Measurement of 24-h urinary sodium excretion identifies non-compliant kidney transplant recipients who need intervention to improve BP control and graft outcome.

Keywords: Graft Survival, Hypertension, Kidney Transplantation, Sodium Chloride

Add Comment 0 Comments

In Press

Original article  

Outcomes of Combined Liver-Kidney Transplantation in Polycystic Liver and Kidney Disease

Ann Transplant In Press; DOI: 10.12659/AOT.947639  

Most Viewed Current Articles

03 Jan 2023 : Original article   6,885

Impact of Autologous Stem Cell Transplantation on Primary Central Nervous System Lymphoma in First-Line and...

DOI :10.12659/AOT.938467

Ann Transplant 2023; 28:e938467

15 Aug 2023 : Review article   6,837

Free-Circulating Nucleic Acids as Biomarkers in Patients After Solid Organ Transplantation

DOI :10.12659/AOT.939750

Ann Transplant 2023; 28:e939750

16 May 2023 : Original article   6,584

Breaking Antimicrobial Resistance: High-Dose Amoxicillin with Clavulanic Acid for Urinary Tract Infections ...

DOI :10.12659/AOT.939258

Ann Transplant 2023; 28:e939258

28 May 2024 : Original article   5,940

Effect of Dexmedetomidine Combined with Remifentanil on Emergence Agitation During Awakening from Sevoflura...

DOI :10.12659/AOT.943281

Ann Transplant 2024; 29:e943281

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358