24 May 2016 : Original article
An Arterial Conduit is Not a Risk Factor for Survival Following Orthotopic Liver Transplantation: An Analysis of 20 Years of Liver Transplantation in Innsbruck
Christian DeneckeBCDEF, Sascha WeissAB, Matthias BieblBC, Josef FritzBCD, Tomasz DziodzioAB, Felix AignerAB, Robert SucherB, Andreas BrandlB, Claudia BösmüllerB, Johann PratschkeA, Robert ÖllingerBCDDOI: 10.12659/AOT.896659
Ann Transplant 2016; 21:321-328
Abstract
BACKGROUND: In adult liver transplantation, arterial conduits have been associated with increased risk for vascular complications and inferior outcome.
MATERIAL AND METHODS: Complication rates and outcomes of adult patients undergoing liver transplantation in our center between 1990 and 2012 were analyzed retrospectively. Characteristics, transplantation-related factors, and survival rates of patients with conduit grafts (n=43) were compared to patients with a standard arterial anastomosis (n=904) by univariate and multivariate analysis.
RESULTS: Patients in the conduit group were younger but had a significantly higher proportion of high-urgency and re-transplantations. While patient survival was comparable between the groups, graft survival was inferior for patients with a conduit (1-year, 5-year, and 10-year survival, control vs. conduit group: 87.3%, 78.8% and 71.5% vs. 72.4%, 63.8%, and 41.8%, respectively, p=0.008). In univariate analysis, an arterial conduit was associated with more arterial and biliary complications. However, an arterial conduit was not an independent risk factor for graft or patient survival in a Cox regression analysis.
CONCLUSIONS: An arterial conduit is associated with more vascular complications, yet a conduit per se does not influence graft survival. The inferior outcome may reflect the complex situation of the sicker liver transplant patients needing a non-standard arterial anastomosis.
Keywords: Anastomosis, Surgical, Liver Transplantation, Patient Outcome Assessment
In Press
Original article
Impact of Donor-Recipient Relationship on Long-Term Outcomes in Living-Related Donor Kidney TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.945065
Original article
Urinary Chemokines CXCL9 and CXCL10 Are Non-Invasive Biomarkers of Kidney Transplant RejectionAnn Transplant In Press; DOI: 10.12659/AOT.944762
Original article
Risk Factors for Graft Failure After Penetrating Keratoplasty in Eastern China from 2018 to 2021Ann Transplant In Press; DOI: 10.12659/AOT.945388
Original article
Predictive Model for Post-Transplant Renal Fibrosis Using Ultrasound Shear Wave ElastographyAnn Transplant In Press; DOI: 10.12659/AOT.945699
Most Viewed Current Articles
05 Apr 2022 : Original article 12,955
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
22 Nov 2022 : Original article 10,017
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
12 Jan 2022 : Original article 9,368
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
15 Mar 2022 : Case report 7,140
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860