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24 May 2016 : Original article  

An Arterial Conduit is Not a Risk Factor for Survival Following Orthotopic Liver Transplantation: An Analysis of 20 Years of Liver Transplantation in Innsbruck

Christian DeneckeBCDEF, Sascha WeissAB, Matthias BieblBC, Josef FritzBCD, Tomasz DziodzioAB, Felix AignerAB, Robert SucherB, Andreas BrandlB, Claudia BösmüllerB, Johann PratschkeA, Robert ÖllingerBCD

DOI: 10.12659/AOT.896659

Ann Transplant 2016; 21:321-328


BACKGROUND: In adult liver transplantation, arterial conduits have been associated with increased risk for vascular complications and inferior outcome.

MATERIAL AND METHODS: Complication rates and outcomes of adult patients undergoing liver transplantation in our center between 1990 and 2012 were analyzed retrospectively. Characteristics, transplantation-related factors, and survival rates of patients with conduit grafts (n=43) were compared to patients with a standard arterial anastomosis (n=904) by univariate and multivariate analysis.

RESULTS: Patients in the conduit group were younger but had a significantly higher proportion of high-urgency and re-transplantations. While patient survival was comparable between the groups, graft survival was inferior for patients with a conduit (1-year, 5-year, and 10-year survival, control vs. conduit group: 87.3%, 78.8% and 71.5% vs. 72.4%, 63.8%, and 41.8%, respectively, p=0.008). In univariate analysis, an arterial conduit was associated with more arterial and biliary complications. However, an arterial conduit was not an independent risk factor for graft or patient survival in a Cox regression analysis.

CONCLUSIONS: An arterial conduit is associated with more vascular complications, yet a conduit per se does not influence graft survival. The inferior outcome may reflect the complex situation of the sicker liver transplant patients needing a non-standard arterial anastomosis.

Keywords: Anastomosis, Surgical, Liver Transplantation, Patient Outcome Assessment



17 June 2022 : Case report  

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Ann Transplant In Press; DOI: 10.12659/AOT.935874  

12 April 2022 : Letter/Correspondence  

Pancreas Allograft Thrombosis as a Post-COVID-19 Complication in a Diabetic Patient After Pancreas Transpla...

Ann Transplant 2022; 27:e935863

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Ann Transplant 2021; 26:e933152

26 October 2021 : Original article  

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Ann Transplant 2021; 26:e933001

In Press

23 Jun 2022 : Original article  

Evaluation of Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program in Comparison to S...

Ann Transplant In Press; DOI: 10.12659/AOT.936514  

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Ann Transplant In Press; DOI: 10.12659/AOT.935874  

20 Jun 2022 : Original article  

The Association Between Tacrolimus Levels and Hyperkalemia in Allograft Recipients Who Underwent Heart or L...

Ann Transplant In Press; DOI: 10.12659/AOT.935607  

15 Jun 2022 : Original article  

Donor CYP3A5 Expression Decreases Renal Transplantation Outcomes in White Renal Transplant Recipients

Ann Transplant In Press; DOI: 10.12659/AOT.936276  

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DOI :10.12659/AOT.934924

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358