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22 April 2024 : Original article  

[In Press] Implementation and Evaluation of Discharge Planning for Patients Undergoing Umbilical Cord Blood Transplantation

Lu Huang ORCID logo12ABCDEFG, Yan Zhu1ABCDEF, Yun Wu1A, Ying-Ying Wang1A, Gui-qi Song3A, Kai-di Song1A, Yao-hua Wu2A, Yong-Liang Zhang4ADG

DOI: 10.12659/AOT.943770

Ann Transplant In Press; DOI: 10.12659/AOT.943770  

Available online: 2024-04-22, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule


Umbilical cord blood transplantation (UCBT) patients have high rates of unplanned readmissions and poor quality of life (QoL). The aim of this study was to evaluate the effects of discharge planning on unplanned readmissions, self-efficacy, QoL, and clinical outcomes.
Patients who received their first UCBT from April 2022 to March 2023 were included. Participants (n=72) were assigned to a control group (CG: received usual care) or an intervention group (IG: received discharge planning from admission to 100 days after UCBT). The cumulative readmission rates 30 days after discharge and 100 days after UCBT were analyzed using the log-rank test. Self-efficacy and QoL were assessed at admission and 100 days after UCBT using the General Self-Efficacy Scale and FACT-BMT version 4, clinical outcomes derived from medical records.
Sixty-six patients completed the study. Discharge planning did not reduce readmission rates 30 days after discharge (20.59% vs 31.25%, P=0.376) or 100 days after UCBT (29.41% vs 34.38%, P=0.629). However, the IG showed significantly better self-efficacy (P<0.001), and except for social and emotional well-being, all the other dimensions and 3 total scores of FACT-BMT in the IG were higher than for the controls at 100 days after UCBT (P<0.05).
The discharge planning program can improve self-efficacy and QoL of UCBT recipients. The implementation of discharge planning for patients undergoing UCBT was necessary for successful hospital-to-home transitions.

Keywords: Stem Cell Transplantation; Quality of Life; Discharge Planning; Hospital Readmissin

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358