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13 April 2026 : Original article  

[In Press] Development and Validation of an Early Post-Liver Transplant Activity Knowledge, Attitude, and Practice Questionnaire for Intensive Care Unit Nurses: A Multicenter Study

Shuo Li1ACEF, Lixia Zhong2BDF, Yulin Zheng3BDF, Yanhong Jin4BDF

DOI: 10.12659/AOT.952175

Ann Transplant In Press; DOI: 10.12659/AOT.952175  

Available online: 2026-04-13, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
We developed and validated a questionnaire assessing intensive care unit (ICU) nurses’ knowledge, attitude, and practice (KAP) regarding early mobilization of patients who are critically ill following liver transplantation.
MATERIAL AND METHODS
Using KAP theory, an initial questionnaire was formed via a literature review, Delphi expert consultation, and pre-survey. In January 2024, ICU nurses from 7 Chinese tertiary hospitals conducting liver transplants were surveyed, yielding 334 valid responses.
RESULTS
The Early Activity Assessment Tools for ICU Nurses after Liver Transplantation Based on the Theory of Knowledge, Attitude, and Practice contains 3 dimensions and 40 entries, including 17 entries in the knowledge dimension, 10 entries in the attitude dimension, and 13 entries in the practice dimension. The content validity index (CVI) of the questionnaire was 0.937, and the CVI of each entry ranged from 0.800 to 1.000. The exploratory factor analysis extracted 3 male factors, accounting for a cumulative variance contribution of 86.852%. The Cronbach’s alpha coefficient of the questionnaire was 0.976, the folded half reliability was 0.772, and the retest reliability was 0.784.
CONCLUSIONS
The reliability of the Early Activity Assessment Tools for ICU Nurses after Liver Transplantation Based on the Theory of Knowledge, Attitude, and Practice is good, and the tool can support the preliminary verification of the knowledge, attitude, and practice level of ICU nurses on early activities of patients who are critically ill following liver transplantation.

Keywords: Liver Transplantation; Nurse Clinicians; Knowledge; Reproducibility of Results

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358