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15 April 2026 : Case report  

[In Press] First Reported Asian Cases of Robot-Assisted Simultaneous Bilateral Nephrectomy With Kidney Transplantation in Autosomal Dominant Polycystic Kidney Disease: A Case Series

Jin-Myung Kim1ABCDEF, Hye Eun Kwon1BC, Youngmin Ko1BD, Joo Hee Jung1ABC, Hyunwook Kwon1DEF, Young Hoon Kim1DEF, Sung Shin ORCID logo1ACDEFG

DOI: 10.12659/AOT.952581

Ann Transplant In Press; DOI: 10.12659/AOT.952581  

Available online: 2026-04-15, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
Autosomal dominant polycystic kidney disease (ADPKD) is frequently associated with massive kidney enlargement, which complicates kidney transplantation by limiting intra-abdominal space. Simultaneous bilateral nephrectomy with kidney transplantation can reduce surgical burden and avoid staged procedures, but it is technically demanding and rarely performed using robotic surgery. No such cases have been reported previously in Asian patients.
CASE REPORT
Two adult patients with end-stage kidney disease due to ADPKD presented with severe abdominal distension, pain, early satiety, and impaired quality of life caused by massively enlarged kidneys extending into the pelvis. Robot-assisted simultaneous bilateral nephrectomy was performed using a transperitoneal approach, followed by living-donor kidney transplantation during the same operation. Despite distorted anatomy, limited working space, and extensive vascular adhesions, robotic nephrectomy allowed precise dissection and safe completion of bilateral kidney removal. After repositioning, graft implantation in the iliac fossa was successfully achieved. Operative times were prolonged (approximately 10 hours and 9 hours), reflecting the complexity of simultaneous bilateral nephrectomy and transplantation, while estimated blood loss remained low and no transfusions were required. Both patients demonstrated immediate graft function, early ambulation, and uneventful recovery without intraoperative or postoperative complications.
CONCLUSIONS
Robot-assisted simultaneous bilateral nephrectomy with kidney transplantation is feasible and safe in selected patients with severely enlarged polycystic kidneys. These first reported Asian cases suggest that this approach may offer perioperative and recovery advantages while avoiding the risks of staged operations.

Keywords: Case Reports; Postoperative Recovery; Robotic Surgical Procedures; Surgical Procedures, Operative; Transplantation

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358