21 May 2024 : Original article
[In Press] Post-Donation Regret and Anxiety Among Family Living Liver Donors: The Mediating Roles of Family Relationships and Sense of Mastery
Ye Sol Lee![ORCID logo](https://jours.isi-science.com/images/id_icon_32.png)
![ORCID logo](https://jours.isi-science.com/images/id_icon_32.png)
![ORCID logo](https://jours.isi-science.com/images/id_icon_32.png)
DOI: 10.12659/AOT.944176
Ann Transplant In Press; DOI: 10.12659/AOT.944176
Available online: 2024-05-21, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Post-donation regret in family living liver donors can impact their mental well-being. This study examined whether the relationship between post-donation regret and anxiety is mediated by family relationships and a sense of mastery.
MATERIAL AND METHODS
We conducted a secondary analysis of de-identified cross-sectional data from a prior study that included 124 living liver donors. These donors underwent partial hepatectomy between January 2011 and March 2021 at a tertiary hospital in Seoul, South Korea. The data included demographic and clinical characteristics, along with the results from administering the following measures: the Post-Donation Regret Scale, Family Relationships Index, Pearlin Mastery Scale, and the Generalized Anxiety Disorder-2 scale.
RESULTS
Among family living liver donors, 5.6% had anxiety after donation. The total effect of post-donation regret on anxiety was significant (B=0.41, p<0.05). However, the direct effect of regret on anxiety was not significant (B=-0.05, p=0.733). Post-donation regret had indirect effects on anxiety, solely through family relationships (B=0.329, 95% CI=0.130, 0.563) and sequentially through family relationships and mastery (B=0.088, 95% CI=0.008, 0.232), even after controlling for sex, age, postoperative complications, years since donation, and recipient’s death. In addition, postoperative complication was a predictor of anxiety (B=0.64, p<0.05).
CONCLUSIONS
Providing family-centered and mastery-enhancing interventions may help alleviate the anxiety of family living liver donors.
Keywords: Anxiety; Emotions; Family Relations; Liver Transplantation; Living Donors
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